Wang J - Search Results

1

Soluble human urokinase receptor is composed of two active units.

Higazi AA, Mazar A, Wang J, Quan N, Griffin R, Reilly R, Henkin J, Cines DB. Higazi AA, et al. Among authors: wang j. J Biol Chem. 1997 Feb 21;272(8):5348-53. doi: 10.1074/jbc.272.8.5348. J Biol Chem. 1997. PMID: 9030610 Free article.

2

Single-chain urokinase-type plasminogen activator bound to its receptor is relatively resistant to plasminogen activator inhibitor type 1.

Higazi AA, Mazar A, Wang J, Reilly R, Henkin J, Kniss D, Cines D. Higazi AA, et al. Among authors: wang j. Blood. 1996 May 1;87(9):3545-9. Blood. 1996. PMID: 8611676 Free article.

3

Plasminogen activation by pro-urokinase in complex with its receptor--dependence on a tripeptide (Spectrozyme plasmin).

Wang J, Mazar A, Quan N, Schneider A, Henkin J. Wang J, et al. Eur J Biochem. 1997 Jul 1;247(1):256-61. doi: 10.1111/j.1432-1033.1997.00256.x. Eur J Biochem. 1997. PMID: 9249034 Free article.

4

Binding of high molecular weight kininogen to human endothelial cells is mediated via a site within domains 2 and 3 of the urokinase receptor.

Colman RW, Pixley RA, Najamunnisa S, Yan W, Wang J, Mazar A, McCrae KR. Colman RW, et al. Among authors: wang j. J Clin Invest. 1997 Sep 15;100(6):1481-7. doi: 10.1172/JCI119669. J Clin Invest. 1997. PMID: 9294114 Free PMC article.

5

Re-engineering of human urokinase provides a system for structure-based drug design at high resolution and reveals a novel structural subsite.

Nienaber V, Wang J, Davidson D, Henkin J. Nienaber V, et al. Among authors: wang j. J Biol Chem. 2000 Mar 10;275(10):7239-48. doi: 10.1074/jbc.275.10.7239. J Biol Chem. 2000. PMID: 10702294 Free article.

6

Structure-directed discovery of potent non-peptidic inhibitors of human urokinase that access a novel binding subsite.

Nienaber VL, Davidson D, Edalji R, Giranda VL, Klinghofer V, Henkin J, Magdalinos P, Mantei R, Merrick S, Severin JM, Smith RA, Stewart K, Walter K, Wang J, Wendt M, Weitzberg M, Zhao X, Rockway T. Nienaber VL, et al. Among authors: wang j. Structure. 2000 May 15;8(5):553-63. doi: 10.1016/s0969-2126(00)00136-2. Structure. 2000. PMID: 10801494 Free article.

7

Selective inhibition of endothelial cell proliferation by fumagillin is not due to differential expression of methionine aminopeptidases.

Wang J, Lou P, Henkin J. Wang J, et al. J Cell Biochem. 2000 Apr;77(3):465-73. J Cell Biochem. 2000. PMID: 10760954

8

Paclitaxel at ultra low concentrations inhibits angiogenesis without affecting cellular microtubule assembly.

Wang J, Lou P, Lesniewski R, Henkin J. Wang J, et al. Anticancer Drugs. 2003 Jan;14(1):13-9. doi: 10.1097/00001813-200301000-00003. Anticancer Drugs. 2003. PMID: 12544254

9

3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2.

Sheppard GS, Wang J, Kawai M, BaMaung NY, Craig RA, Erickson SA, Lynch L, Patel J, Yang F, Searle XB, Lou P, Park C, Kim KH, Henkin J, Lesniewski R. Sheppard GS, et al. Among authors: wang j. Bioorg Med Chem Lett. 2004 Feb 23;14(4):865-8. doi: 10.1016/j.bmcl.2003.12.031. Bioorg Med Chem Lett. 2004. PMID: 15012983

10

Discovery and optimization of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2: a structural basis for the reduction of albumin binding.

Sheppard GS, Wang J, Kawai M, Fidanze SD, BaMaung NY, Erickson SA, Barnes DM, Tedrow JS, Kolaczkowski L, Vasudevan A, Park DC, Wang GT, Sanders WJ, Mantei RA, Palazzo F, Tucker-Garcia L, Lou P, Zhang Q, Park CH, Kim KH, Petros A, Olejniczak E, Nettesheim D, Hajduk P, Henkin J, Lesniewski R, Davidsen SK, Bell RL. Sheppard GS, et al. Among authors: wang gt, wang j. J Med Chem. 2006 Jun 29;49(13):3832-49. doi: 10.1021/jm0601001. J Med Chem. 2006. PMID: 16789740

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