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Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis.
Cabezas-Wallscheid N, Klimmeck D, Hansson J, Lipka DB, Reyes A, Wang Q, Weichenhan D, Lier A, von Paleske L, Renders S, Wünsche P, Zeisberger P, Brocks D, Gu L, Herrmann C, Haas S, Essers MAG, Brors B, Eils R, Huber W, Milsom MD, Plass C, Krijgsveld J, Trumpp A. Cabezas-Wallscheid N, et al. Among authors: wang q. Cell Stem Cell. 2014 Oct 2;15(4):507-522. doi: 10.1016/j.stem.2014.07.005. Epub 2014 Aug 21. Cell Stem Cell. 2014. PMID: 25158935 Free article.
Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations.
Rausch T, Jones DT, Zapatka M, Stütz AM, Zichner T, Weischenfeldt J, Jäger N, Remke M, Shih D, Northcott PA, Pfaff E, Tica J, Wang Q, Massimi L, Witt H, Bender S, Pleier S, Cin H, Hawkins C, Beck C, von Deimling A, Hans V, Brors B, Eils R, Scheurlen W, Blake J, Benes V, Kulozik AE, Witt O, Martin D, Zhang C, Porat R, Merino DM, Wasserman J, Jabado N, Fontebasso A, Bullinger L, Rücker FG, Döhner K, Döhner H, Koster J, Molenaar JJ, Versteeg R, Kool M, Tabori U, Malkin D, Korshunov A, Taylor MD, Lichter P, Pfister SM, Korbel JO. Rausch T, et al. Among authors: wang q. Cell. 2012 Jan 20;148(1-2):59-71. doi: 10.1016/j.cell.2011.12.013. Cell. 2012. PMID: 22265402 Free PMC article.
Tagmentation-based whole-genome bisulfite sequencing.
Wang Q, Gu L, Adey A, Radlwimmer B, Wang W, Hovestadt V, Bähr M, Wolf S, Shendure J, Eils R, Plass C, Weichenhan D. Wang Q, et al. Among authors: wang w. Nat Protoc. 2013 Oct;8(10):2022-32. doi: 10.1038/nprot.2013.118. Epub 2013 Sep 26. Nat Protoc. 2013. PMID: 24071908
Identification of DNA methylation changes at cis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulfite sequencing.
Lipka DB, Wang Q, Cabezas-Wallscheid N, Klimmeck D, Weichenhan D, Herrmann C, Lier A, Brocks D, von Paleske L, Renders S, Wünsche P, Zeisberger P, Gu L, Haas S, Essers MA, Brors B, Eils R, Trumpp A, Milsom MD, Plass C. Lipka DB, et al. Among authors: wang q. Cell Cycle. 2014;13(22):3476-87. doi: 10.4161/15384101.2014.973334. Cell Cycle. 2014. PMID: 25483069 Free PMC article.
DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia.
Oakes CC, Seifert M, Assenov Y, Gu L, Przekopowitz M, Ruppert AS, Wang Q, Imbusch CD, Serva A, Koser SD, Brocks D, Lipka DB, Bogatyrova O, Weichenhan D, Brors B, Rassenti L, Kipps TJ, Mertens D, Zapatka M, Lichter P, Döhner H, Küppers R, Zenz T, Stilgenbauer S, Byrd JC, Plass C. Oakes CC, et al. Among authors: wang q. Nat Genet. 2016 Mar;48(3):253-64. doi: 10.1038/ng.3488. Epub 2016 Jan 18. Nat Genet. 2016. PMID: 26780610 Free PMC article.
Environment-induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children.
Bauer T, Trump S, Ishaque N, Thürmann L, Gu L, Bauer M, Bieg M, Gu Z, Weichenhan D, Mallm JP, Röder S, Herberth G, Takada E, Mücke O, Winter M, Junge KM, Grützmann K, Rolle-Kampczyk U, Wang Q, Lawerenz C, Borte M, Polte T, Schlesner M, Schanne M, Wiemann S, Geörg C, Stunnenberg HG, Plass C, Rippe K, Mizuguchi J, Herrmann C, Eils R, Lehmann I. Bauer T, et al. Among authors: wang q. Mol Syst Biol. 2016 Mar 24;12(3):861. doi: 10.15252/msb.20156520. Mol Syst Biol. 2016. PMID: 27013061 Free PMC article.
Maternal phthalate exposure promotes allergic airway inflammation over 2 generations through epigenetic modifications.
Jahreis S, Trump S, Bauer M, Bauer T, Thürmann L, Feltens R, Wang Q, Gu L, Grützmann K, Röder S, Averbeck M, Weichenhan D, Plass C, Sack U, Borte M, Dubourg V, Schüürmann G, Simon JC, von Bergen M, Hackermüller J, Eils R, Lehmann I, Polte T. Jahreis S, et al. Among authors: wang q. J Allergy Clin Immunol. 2018 Feb;141(2):741-753. doi: 10.1016/j.jaci.2017.03.017. Epub 2017 Apr 6. J Allergy Clin Immunol. 2018. PMID: 28392331 Free article.
Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues.
Delacher M, Imbusch CD, Weichenhan D, Breiling A, Hotz-Wagenblatt A, Träger U, Hofer AC, Kägebein D, Wang Q, Frauhammer F, Mallm JP, Bauer K, Herrmann C, Lang PA, Brors B, Plass C, Feuerer M. Delacher M, et al. Among authors: wang q. Nat Immunol. 2017 Oct;18(10):1160-1172. doi: 10.1038/ni.3799. Epub 2017 Aug 7. Nat Immunol. 2017. PMID: 28783152 Free PMC article.
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