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DOT1L inhibitors block abnormal self-renewal induced by cohesin loss.
Heimbruch KE, Fisher JB, Stelloh CT, Phillips E, Reimer MH Jr, Wargolet AJ, Meyer AE, Pulakanti K, Viny AD, Loppnow JJ, Levine RL, Pulikkan JA, Zhu N, Rao S. Heimbruch KE, et al. Among authors: wargolet aj. Sci Rep. 2021 Mar 31;11(1):7288. doi: 10.1038/s41598-021-86646-9. Sci Rep. 2021. PMID: 33790356 Free PMC article.
A-C Estrogens as Potent and Selective Estrogen Receptor-Beta Agonists (SERBAs) to Enhance Memory Consolidation under Low-Estrogen Conditions.
Hanson AM, Perera KLIS, Kim J, Pandey RK, Sweeney N, Lu X, Imhoff A, Mackinnon AC, Wargolet AJ, Van Hart RM, Frick KM, Donaldson WA, Sem DS. Hanson AM, et al. Among authors: wargolet aj. J Med Chem. 2018 Jun 14;61(11):4720-4738. doi: 10.1021/acs.jmedchem.7b01601. Epub 2018 Jun 4. J Med Chem. 2018. PMID: 29741891 Free PMC article.