Wayne AS - Search Results

1

Cytotoxicity of the anti-CD22 immunotoxin HA22 (CAT-8015) against paediatric acute lymphoblastic leukaemia.

Mussai F, Campana D, Bhojwani D, Stetler-Stevenson M, Steinberg SM, Wayne AS, Pastan I. Mussai F, et al. Among authors: wayne as. Br J Haematol. 2010 Aug;150(3):352-8. doi: 10.1111/j.1365-2141.2010.08251.x. Epub 2010 Jun 7. Br J Haematol. 2010. PMID: 20528877 Free PMC article.

2

Anti-CD22-chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia.

Haso W, Lee DW, Shah NN, Stetler-Stevenson M, Yuan CM, Pastan IH, Dimitrov DS, Morgan RA, FitzGerald DJ, Barrett DM, Wayne AS, Mackall CL, Orentas RJ. Haso W, et al. Among authors: wayne as. Blood. 2013 Feb 14;121(7):1165-74. doi: 10.1182/blood-2012-06-438002. Epub 2012 Dec 14. Blood. 2013. PMID: 23243285 Free PMC article.

3

Phase 1 study of the anti-CD22 immunotoxin moxetumomab pasudotox for childhood acute lymphoblastic leukemia.

Wayne AS, Shah NN, Bhojwani D, Silverman LB, Whitlock JA, Stetler-Stevenson M, Sun W, Liang M, Yang J, Kreitman RJ, Lanasa MC, Pastan I. Wayne AS, et al. Blood. 2017 Oct 5;130(14):1620-1627. doi: 10.1182/blood-2017-02-749101. Epub 2017 Aug 9. Blood. 2017. PMID: 28983018 Free PMC article. Clinical Trial.

4

Anti-CD22 immunotoxin RFB4(dsFv)-PE38 (BL22) for CD22-positive hematologic malignancies of childhood: preclinical studies and phase I clinical trial.

Wayne AS, Kreitman RJ, Findley HW, Lew G, Delbrook C, Steinberg SM, Stetler-Stevenson M, Fitzgerald DJ, Pastan I. Wayne AS, et al. Clin Cancer Res. 2010 Mar 15;16(6):1894-903. doi: 10.1158/1078-0432.CCR-09-2980. Epub 2010 Mar 9. Clin Cancer Res. 2010. PMID: 20215554 Free PMC article. Clinical Trial.

5

Enhancing immunotoxin cell-killing activity via combination therapy with ABT-737.

Fitzgerald DJ, Moskatel E, Ben-Josef G, Traini R, Tendler T, Sharma A, Antignani A, Mussai F, Wayne A, Kreitman RJ, Pastan I. Fitzgerald DJ, et al. Leuk Lymphoma. 2011 Jun;52 Suppl 2(Suppl 2):79-81. doi: 10.3109/10428194.2011.569961. Leuk Lymphoma. 2011. PMID: 21599608 Free PMC article. Review.

6

Methylation of the DPH1 promoter causes immunotoxin resistance in acute lymphoblastic leukemia cell line KOPN-8.

Hu X, Wei H, Xiang L, Chertov O, Wayne AS, Bera TK, Pastan I. Hu X, et al. Among authors: wayne as. Leuk Res. 2013 Nov;37(11):1551-6. doi: 10.1016/j.leukres.2013.08.005. Epub 2013 Aug 13. Leuk Res. 2013. PMID: 24070652 Free PMC article.

7

T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial.

Lee DW, Kochenderfer JN, Stetler-Stevenson M, Cui YK, Delbrook C, Feldman SA, Fry TJ, Orentas R, Sabatino M, Shah NN, Steinberg SM, Stroncek D, Tschernia N, Yuan C, Zhang H, Zhang L, Rosenberg SA, Wayne AS, Mackall CL. Lee DW, et al. Among authors: wayne as. Lancet. 2015 Feb 7;385(9967):517-528. doi: 10.1016/S0140-6736(14)61403-3. Epub 2014 Oct 13. Lancet. 2015. PMID: 25319501 Free PMC article. Clinical Trial.

8

Characterization of CD22 expression in acute lymphoblastic leukemia.

Shah NN, Stevenson MS, Yuan CM, Richards K, Delbrook C, Kreitman RJ, Pastan I, Wayne AS. Shah NN, et al. Among authors: wayne as. Pediatr Blood Cancer. 2015 Jun;62(6):964-9. doi: 10.1002/pbc.25410. Epub 2015 Mar 1. Pediatr Blood Cancer. 2015. PMID: 25728039 Free PMC article.

9

Protein Kinase Inhibitor H89 Enhances the Activity of Pseudomonas Exotoxin A-Based Immunotoxins.

Liu X, Müller F, Wayne AS, Pastan I. Liu X, et al. Among authors: wayne as. Mol Cancer Ther. 2016 May;15(5):1053-62. doi: 10.1158/1535-7163.MCT-15-0828. Epub 2016 Mar 3. Mol Cancer Ther. 2016. PMID: 26939705 Free PMC article.

10

Wide Variability in the Time Required for Immunotoxins to Kill B Lineage Acute Lymphoblastic Leukemia Cells: Implications for Trial Design.

Müller F, Cunningham T, Liu XF, Wayne AS, Pastan I. Müller F, et al. Among authors: wayne as. Clin Cancer Res. 2016 Oct 1;22(19):4913-4922. doi: 10.1158/1078-0432.CCR-15-2500. Epub 2016 Apr 25. Clin Cancer Res. 2016. PMID: 27114443 Free PMC article.

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