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Off-Target drug effects resulting in altered gene expression events with epigenetic and "Quasi-Epigenetic" origins.
Anderson SJ, Feye KM, Schmidt-McCormack GR, Malovic E, Mlynarczyk GSA, Izbicki P, Arnold LF, Jefferson MA, de la Rosa BM, Wehrman RF, Luna KC, Hu HZ, Kondru NC, Kleinhenz MD, Smith JS, Manne S, Putra MR, Choudhary S, Massey N, Luo D, Berg CA, Acharya S, Sharma S, Kanuri SH, Lange JK, Carlson SA. Anderson SJ, et al. Among authors: wehrman rf. Pharmacol Res. 2016 May;107:229-233. doi: 10.1016/j.phrs.2016.03.028. Epub 2016 Mar 26. Pharmacol Res. 2016. PMID: 27025785 Review.
MG53 promotes corneal wound healing and mitigates fibrotic remodeling in rodents.
Chandler HL, Tan T, Yang C, Gemensky-Metzler AJ, Wehrman RF, Jiang Q, Peterson CMW, Geng B, Zhou X, Wang Q, Kaili D, Adesanya TMA, Yi F, Zhu H, Ma J. Chandler HL, et al. Among authors: wehrman rf. Commun Biol. 2019 Feb 20;2:71. doi: 10.1038/s42003-019-0316-7. eCollection 2019. Commun Biol. 2019. PMID: 30793049 Free PMC article.