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Reset of Inflammatory Priming of Joint Tissue and Reduction of the Severity of Arthritis Flares by Bromodomain Inhibition.
Friščić J, Reinwald C, Böttcher M, Houtman M, Euler M, Chen X, Walker KI, Kirchner P, Zhu H, Wirth B, Weidner D, Krüger R, Trajkovic V, Ekici AB, Klein K, Mougiakakos D, Ospelt C, Schett G, Hoffmann MH. Friščić J, et al. Among authors: weidner d. Arthritis Rheumatol. 2023 Apr;75(4):517-532. doi: 10.1002/art.42378. Epub 2023 Feb 2. Arthritis Rheumatol. 2023. PMID: 36245290 Free article.
Treatment with DNAse I fosters binding to nec PBMC of CRP.
Janko C, Schorn C, Weidner D, Sarter K, Chaurio R, Sheriff A, Schett G, Munoz LE. Janko C, et al. Among authors: weidner d. Autoimmunity. 2009 May;42(4):286-8. doi: 10.1080/08916930902828197. Autoimmunity. 2009. PMID: 19811278
Nanoparticles size-dependently initiate self-limiting NETosis-driven inflammation.
Muñoz LE, Bilyy R, Biermann MH, Kienhöfer D, Maueröder C, Hahn J, Brauner JM, Weidner D, Chen J, Scharin-Mehlmann M, Janko C, Friedrich RP, Mielenz D, Dumych T, Lootsik MD, Schauer C, Schett G, Hoffmann M, Zhao Y, Herrmann M. Muñoz LE, et al. Among authors: weidner d. Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):E5856-E5865. doi: 10.1073/pnas.1602230113. Epub 2016 Sep 19. Proc Natl Acad Sci U S A. 2016. PMID: 27647892 Free PMC article.
Oxidative Burst-Dependent NETosis Is Implicated in the Resolution of Necrosis-Associated Sterile Inflammation.
Biermann MH, Podolska MJ, Knopf J, Reinwald C, Weidner D, Maueröder C, Hahn J, Kienhöfer D, Barras A, Boukherroub R, Szunerits S, Bilyy R, Hoffmann M, Zhao Y, Schett G, Herrmann M, Munoz LE. Biermann MH, et al. Among authors: weidner d. Front Immunol. 2016 Dec 1;7:557. doi: 10.3389/fimmu.2016.00557. eCollection 2016. Front Immunol. 2016. PMID: 27990145 Free PMC article.
Aggregated neutrophil extracellular traps resolve inflammation by proteolysis of cytokines and chemokines and protection from antiproteases.
Hahn J, Schauer C, Czegley C, Kling L, Petru L, Schmid B, Weidner D, Reinwald C, Biermann MHC, Blunder S, Ernst J, Lesner A, Bäuerle T, Palmisano R, Christiansen S, Herrmann M, Bozec A, Gruber R, Schett G, Hoffmann MH. Hahn J, et al. Among authors: weidner d. FASEB J. 2019 Jan;33(1):1401-1414. doi: 10.1096/fj.201800752R. Epub 2018 Aug 21. FASEB J. 2019. PMID: 30130433 Free PMC article.
., Schauer, C., Czegley, C., Kling, L., Petru, L., Schmid, B., Weidner, D., Reinwald, C., Biermann, M. H. C., Blunder, S., Ernst, J., Lesner, A., Bauerle, T., Palmisano, R., Christiansen, S., Herrmann, M., Bozec, A., Gruber, R., Schett, G., Hoffmann, M. ...
., Schauer, C., Czegley, C., Kling, L., Petru, L., Schmid, B., Weidner, D., Reinwald, C., Biermann, M. H. C., Blunder, S., Ern …
Locally renewing resident synovial macrophages provide a protective barrier for the joint.
Culemann S, Grüneboom A, Nicolás-Ávila JÁ, Weidner D, Lämmle KF, Rothe T, Quintana JA, Kirchner P, Krljanac B, Eberhardt M, Ferrazzi F, Kretzschmar E, Schicht M, Fischer K, Gelse K, Faas M, Pfeifle R, Ackermann JA, Pachowsky M, Renner N, Simon D, Haseloff RF, Ekici AB, Bäuerle T, Blasig IE, Vera J, Voehringer D, Kleyer A, Paulsen F, Schett G, Hidalgo A, Krönke G. Culemann S, et al. Among authors: weidner d. Nature. 2019 Aug;572(7771):670-675. doi: 10.1038/s41586-019-1471-1. Epub 2019 Aug 7. Nature. 2019. PMID: 31391580 Free PMC article.
105 results