Weinstein H - Search Results

1

Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis.

Li X, Maretzky T, Perez-Aguilar JM, Monette S, Weskamp G, Le Gall S, Beutler B, Weinstein H, Blobel CP. Li X, et al. Among authors: weinstein h. J Cell Sci. 2017 Mar 1;130(5):868-878. doi: 10.1242/jcs.196436. Epub 2017 Jan 19. J Cell Sci. 2017. PMID: 28104813 Free PMC article.

2

A functional selectivity mechanism at the serotonin-2A GPCR involves ligand-dependent conformations of intracellular loop 2.

Perez-Aguilar JM, Shan J, LeVine MV, Khelashvili G, Weinstein H. Perez-Aguilar JM, et al. Among authors: weinstein h. J Am Chem Soc. 2014 Nov 12;136(45):16044-54. doi: 10.1021/ja508394x. Epub 2014 Oct 31. J Am Chem Soc. 2014. PMID: 25314362 Free PMC article.

3

Single-molecule analysis of ligand efficacy in β₂AR-G-protein activation.

Gregorio GG, Masureel M, Hilger D, Terry DS, Juette M, Zhao H, Zhou Z, Perez-Aguilar JM, Hauge M, Mathiasen S, Javitch JA, Weinstein H, Kobilka BK, Blanchard SC. Gregorio GG, et al. Among authors: weinstein h. Nature. 2017 Jul 6;547(7661):68-73. doi: 10.1038/nature22354. Epub 2017 Jun 7. Nature. 2017. PMID: 28607487 Free PMC article.

4

Substrate-selective protein ectodomain shedding by ADAM17 and iRhom2 depends on their juxtamembrane and transmembrane domains.

Tang B, Li X, Maretzky T, Perez-Aguilar JM, McIlwain D, Xie Y, Zheng Y, Mak TW, Weinstein H, Blobel CP. Tang B, et al. Among authors: weinstein h. FASEB J. 2020 Apr;34(4):4956-4969. doi: 10.1096/fj.201902649R. Epub 2020 Feb 26. FASEB J. 2020. PMID: 32103528 Free PMC article.

5

Modeling activated states of GPCRs: the rhodopsin template.

Niv MY, Skrabanek L, Filizola M, Weinstein H. Niv MY, et al. Among authors: weinstein h. J Comput Aided Mol Des. 2006 Jul-Aug;20(7-8):437-48. doi: 10.1007/s10822-006-9061-3. Epub 2006 Nov 11. J Comput Aided Mol Des. 2006. PMID: 17103019 Free PMC article.

6

The mechanism of a neurotransmitter:sodium symporter--inward release of Na+ and substrate is triggered by substrate in a second binding site.

Shi L, Quick M, Zhao Y, Weinstein H, Javitch JA. Shi L, et al. Among authors: weinstein h. Mol Cell. 2008 Jun 20;30(6):667-77. doi: 10.1016/j.molcel.2008.05.008. Mol Cell. 2008. PMID: 18570870 Free PMC article.

7

The cost of living in the membrane: a case study of hydrophobic mismatch for the multi-segment protein LeuT.

Mondal S, Khelashvili G, Shi L, Weinstein H. Mondal S, et al. Among authors: weinstein h. Chem Phys Lipids. 2013 Apr;169:27-38. doi: 10.1016/j.chemphyslip.2013.01.006. Epub 2013 Jan 30. Chem Phys Lipids. 2013. PMID: 23376428 Free PMC article.

8

How the dynamic properties and functional mechanisms of GPCRs are modulated by their coupling to the membrane environment.

Mondal S, Khelashvili G, Johner N, Weinstein H. Mondal S, et al. Among authors: weinstein h. Adv Exp Med Biol. 2014;796:55-74. doi: 10.1007/978-94-007-7423-0_4. Adv Exp Med Biol. 2014. PMID: 24158801 Review.

9

Not just an oil slick: how the energetics of protein-membrane interactions impacts the function and organization of transmembrane proteins.

Mondal S, Khelashvili G, Weinstein H. Mondal S, et al. Among authors: weinstein h. Biophys J. 2014 Jun 3;106(11):2305-16. doi: 10.1016/j.bpj.2014.04.032. Biophys J. 2014. PMID: 24896109 Free PMC article. Review.

10

A Markov State-based Quantitative Kinetic Model of Sodium Release from the Dopamine Transporter.

Razavi AM, Khelashvili G, Weinstein H. Razavi AM, et al. Among authors: weinstein h. Sci Rep. 2017 Jan 6;7:40076. doi: 10.1038/srep40076. Sci Rep. 2017. PMID: 28059145 Free PMC article.

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