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Oxygen-dependent ATF-4 stability is mediated by the PHD3 oxygen sensor.
Köditz J, Nesper J, Wottawa M, Stiehl DP, Camenisch G, Franke C, Myllyharju J, Wenger RH, Katschinski DM. Köditz J, et al. Among authors: wenger rh. Blood. 2007 Nov 15;110(10):3610-7. doi: 10.1182/blood-2007-06-094441. Epub 2007 Aug 7. Blood. 2007. PMID: 17684156 Free article.
Vitamin C is dispensable for oxygen sensing in vivo.
Nytko KJ, Maeda N, Schläfli P, Spielmann P, Wenger RH, Stiehl DP. Nytko KJ, et al. Among authors: wenger rh. Blood. 2011 May 19;117(20):5485-93. doi: 10.1182/blood-2010-09-307637. Epub 2011 Feb 23. Blood. 2011. PMID: 21346252 Free PMC article.
201 results