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HIF1A signaling selectively supports proliferation of breast cancer in the brain.
Ebright RY, Zachariah MA, Micalizzi DS, Wittner BS, Niederhoffer KL, Nieman LT, Chirn B, Wiley DF, Wesley B, Shaw B, Nieblas-Bedolla E, Atlas L, Szabolcs A, Iafrate AJ, Toner M, Ting DT, Brastianos PK, Haber DA, Maheswaran S. Ebright RY, et al. Among authors: wesley b. Nat Commun. 2020 Dec 9;11(1):6311. doi: 10.1038/s41467-020-20144-w. Nat Commun. 2020. PMID: 33298946 Free PMC article.
Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis.
Ebright RY, Lee S, Wittner BS, Niederhoffer KL, Nicholson BT, Bardia A, Truesdell S, Wiley DF, Wesley B, Li S, Mai A, Aceto N, Vincent-Jordan N, Szabolcs A, Chirn B, Kreuzer J, Comaills V, Kalinich M, Haas W, Ting DT, Toner M, Vasudevan S, Haber DA, Maheswaran S, Micalizzi DS. Ebright RY, et al. Among authors: wesley b. Science. 2020 Mar 27;367(6485):1468-1473. doi: 10.1126/science.aay0939. Epub 2020 Feb 6. Science. 2020. PMID: 32029688 Free PMC article.
Blood-based monitoring identifies acquired and targetable driver HER2 mutations in endocrine-resistant metastatic breast cancer.
Medford AJ, Dubash TD, Juric D, Spring L, Niemierko A, Vidula N, Peppercorn J, Isakoff S, Reeves BA, LiCausi JA, Wesley B, Malvarosa G, Yuen M, Wittner BS, Lawrence MS, Iafrate AJ, Ellisen L, Moy B, Toner M, Maheswaran S, Haber DA, Bardia A. Medford AJ, et al. Among authors: wesley b. NPJ Precis Oncol. 2019 Jul 16;3:18. doi: 10.1038/s41698-019-0090-5. eCollection 2019. NPJ Precis Oncol. 2019. PMID: 31341951 Free PMC article.
The Lipogenic Regulator SREBP2 Induces Transferrin in Circulating Melanoma Cells and Suppresses Ferroptosis.
Hong X, Roh W, Sullivan RJ, Wong KHK, Wittner BS, Guo H, Dubash TD, Sade-Feldman M, Wesley B, Horwitz E, Boland GM, Marvin DL, Bonesteel T, Lu C, Aguet F, Burr R, Freeman SS, Parida L, Calhoun K, Jewett MK, Nieman LT, Hacohen N, Näär AM, Ting DT, Toner M, Stott SL, Getz G, Maheswaran S, Haber DA. Hong X, et al. Among authors: wesley b. Cancer Discov. 2021 Mar;11(3):678-695. doi: 10.1158/2159-8290.CD-19-1500. Epub 2020 Nov 17. Cancer Discov. 2021. PMID: 33203734 Free PMC article.
NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer.
Guo H, Golczer G, Wittner BS, Langenbucher A, Zachariah M, Dubash TD, Hong X, Comaills V, Burr R, Ebright RY, Horwitz E, Vuille JA, Hajizadeh S, Wiley DF, Reeves BA, Zhang JM, Niederhoffer KL, Lu C, Wesley B, Ho U, Nieman LT, Toner M, Vasudevan S, Zou L, Mostoslavsky R, Maheswaran S, Lawrence MS, Haber DA. Guo H, et al. Among authors: wesley b. Mol Cell. 2021 Oct 7;81(19):4041-4058.e15. doi: 10.1016/j.molcel.2021.09.016. Mol Cell. 2021. PMID: 34624217 Free PMC article.
Four decades of progress in heart-lung transplantation: Two hundred seventy-one cases at a single institution.
Elde S, Baccouche BM, Mullis DM, Leipzig MM, Deuse T, Krishnan A, Fawad M, Dale R, Walsh S, Padilla-Lopez A, Wesley B, He H, Yajima S, Zhu Y, Wang H, Guenthart BA, Shudo Y, Reitz BA, Woo YJ. Elde S, et al. Among authors: wesley b. J Thorac Cardiovasc Surg. 2024 Feb 5:S0022-5223(24)00100-4. doi: 10.1016/j.jtcvs.2024.01.042. Online ahead of print. J Thorac Cardiovasc Surg. 2024. PMID: 38320627
CRISPRmap: Sequencing-free optical pooled screens mapping multi-omic phenotypes in cells and tissue.
Gu J, Iyer A, Wesley B, Taglialatela A, Leuzzi G, Hangai S, Decker A, Gu R, Klickstein N, Shuai Y, Jankovic K, Parker-Burns L, Jin Y, Zhang JY, Hong J, Niu S, Chou J, Landau DA, Azizi E, Chan EM, Ciccia A, Gaublomme JT. Gu J, et al. Among authors: wesley b. bioRxiv [Preprint]. 2023 Dec 26:2023.12.26.572587. doi: 10.1101/2023.12.26.572587. bioRxiv. 2023. PMID: 38234835 Free PMC article. Preprint.
Single-cell atlas of human liver development reveals pathways directing hepatic cell fates.
Wesley BT, Ross ADB, Muraro D, Miao Z, Saxton S, Tomaz RA, Morell CM, Ridley K, Zacharis ED, Petrus-Reurer S, Kraiczy J, Mahbubani KT, Brown S, Garcia-Bernardo J, Alsinet C, Gaffney D, Horsfall D, Tysoe OC, Botting RA, Stephenson E, Popescu DM, MacParland S, Bader G, McGilvray ID, Ortmann D, Sampaziotis F, Saeb-Parsy K, Haniffa M, Stevens KR, Zilbauer M, Teichmann SA, Vallier L. Wesley BT, et al. Nat Cell Biol. 2022 Oct;24(10):1487-1498. doi: 10.1038/s41556-022-00989-7. Epub 2022 Sep 15. Nat Cell Biol. 2022. PMID: 36109670
Generation of functional hepatocytes by forward programming with nuclear receptors.
Tomaz RA, Zacharis ED, Bachinger F, Wurmser A, Yamamoto D, Petrus-Reurer S, Morell CM, Dziedzicka D, Wesley BT, Geti I, Segeritz CP, de Brito MC, Chhatriwala M, Ortmann D, Saeb-Parsy K, Vallier L. Tomaz RA, et al. Among authors: wesley bt. Elife. 2022 Aug 12;11:e71591. doi: 10.7554/eLife.71591. Elife. 2022. PMID: 35959725 Free PMC article.
26 results