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Cholangiocyte organoids can repair bile ducts after transplantation in the human liver.
Science. 2021 Feb 19;371(6531):839-846. doi: 10.1126/science.aaz6964.
Science. 2021.
PMID: 33602855
Free PMC article.
Regional Differences in Human Biliary Tissues and Corresponding In Vitro-Derived Organoids.
Rimland CA, Tilson SG, Morell CM, Tomaz RA, Lu WY, Adams SE, Georgakopoulos N, Otaizo-Carrasquero F, Myers TG, Ferdinand JR, Gieseck RL 3rd, Sampaziotis F, Tysoe OC, Ross A, Kraiczy JM, Wesley B, Muraro D, Zilbauer M, Oniscu GC, Hannan NRF, Forbes SJ, Saeb-Parsy K, Wynn TA, Vallier L.
Rimland CA, et al.
Hepatology. 2021 Jan;73(1):247-267. doi: 10.1002/hep.31252.
Hepatology. 2021.
PMID: 32222998
Free PMC article.
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Naive Pluripotent Stem Cells Exhibit Phenotypic Variability that Is Driven by Genetic Variation.
Ortmann D, Brown S, Czechanski A, Aydin S, Muraro D, Huang Y, Tomaz RA, Osnato A, Canu G, Wesley BT, Skelly DA, Stegle O, Choi T, Churchill GA, Baker CL, Rugg-Gunn PJ, Munger SC, Reinholdt LG, Vallier L.
Ortmann D, et al. Among authors: wesley bt.
Cell Stem Cell. 2020 Sep 3;27(3):470-481.e6. doi: 10.1016/j.stem.2020.07.019. Epub 2020 Aug 13.
Cell Stem Cell. 2020.
PMID: 32795399
Free PMC article.
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Single-cell atlas of human liver development reveals pathways directing hepatic cell fates.
Wesley BT, Ross ADB, Muraro D, Miao Z, Saxton S, Tomaz RA, Morell CM, Ridley K, Zacharis ED, Petrus-Reurer S, Kraiczy J, Mahbubani KT, Brown S, Garcia-Bernardo J, Alsinet C, Gaffney D, Horsfall D, Tysoe OC, Botting RA, Stephenson E, Popescu DM, MacParland S, Bader G, McGilvray ID, Ortmann D, Sampaziotis F, Saeb-Parsy K, Haniffa M, Stevens KR, Zilbauer M, Teichmann SA, Vallier L.
Wesley BT, et al.
Nat Cell Biol. 2022 Oct;24(10):1487-1498. doi: 10.1038/s41556-022-00989-7. Epub 2022 Sep 15.
Nat Cell Biol. 2022.
PMID: 36109670
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TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells.
Osnato A, Brown S, Krueger C, Andrews S, Collier AJ, Nakanoh S, Quiroga Londoño M, Wesley BT, Muraro D, Brumm AS, Niakan KK, Vallier L, Ortmann D, Rugg-Gunn PJ.
Osnato A, et al. Among authors: wesley bt.
Elife. 2021 Aug 31;10:e67259. doi: 10.7554/eLife.67259.
Elife. 2021.
PMID: 34463252
Free PMC article.
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Generation of functional hepatocytes by forward programming with nuclear receptors.
Tomaz RA, Zacharis ED, Bachinger F, Wurmser A, Yamamoto D, Petrus-Reurer S, Morell CM, Dziedzicka D, Wesley BT, Geti I, Segeritz CP, de Brito MC, Chhatriwala M, Ortmann D, Saeb-Parsy K, Vallier L.
Tomaz RA, et al. Among authors: wesley bt.
Elife. 2022 Aug 12;11:e71591. doi: 10.7554/eLife.71591.
Elife. 2022.
PMID: 35959725
Free PMC article.
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