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M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss.
Bradley SJ, Bourgognon JM, Sanger HE, Verity N, Mogg AJ, White DJ, Butcher AJ, Moreno JA, Molloy C, Macedo-Hatch T, Edwards JM, Wess J, Pawlak R, Read DJ, Sexton PM, Broad LM, Steinert JR, Mallucci GR, Christopoulos A, Felder CC, Tobin AB. Bradley SJ, et al. Among authors: wess j. J Clin Invest. 2017 Feb 1;127(2):487-499. doi: 10.1172/JCI87526. Epub 2016 Dec 19. J Clin Invest. 2017. PMID: 27991860 Free PMC article.
Elucidating the role of muscarinic receptors in psychosis.
Felder CC, Porter AC, Skillman TL, Zhang L, Bymaster FP, Nathanson NM, Hamilton SE, Gomeza J, Wess J, McKinzie DL. Felder CC, et al. Among authors: wess j. Life Sci. 2001 Apr 27;68(22-23):2605-13. doi: 10.1016/s0024-3205(01)01059-1. Life Sci. 2001. PMID: 11392633
M1 muscarinic receptor signaling in mouse hippocampus and cortex.
Porter AC, Bymaster FP, DeLapp NW, Yamada M, Wess J, Hamilton SE, Nathanson NM, Felder CC. Porter AC, et al. Among authors: wess j. Brain Res. 2002 Jul 19;944(1-2):82-9. doi: 10.1016/s0006-8993(02)02721-x. Brain Res. 2002. PMID: 12106668
348 results