Wess J - Search Results

1

Mapping of single amino acid residues required for selective activation of Gq/11 by the m3 muscarinic acetylcholine receptor.

Blin N, Yun J, Wess J. Blin N, et al. Among authors: wess j. J Biol Chem. 1995 Jul 28;270(30):17741-8. doi: 10.1074/jbc.270.30.17741. J Biol Chem. 1995. PMID: 7629074 Free article.

2

Role of conserved threonine and tyrosine residues in acetylcholine binding and muscarinic receptor activation. A study with m3 muscarinic receptor point mutants.

Wess J, Maggio R, Palmer JR, Vogel Z. Wess J, et al. J Biol Chem. 1992 Sep 25;267(27):19313-9. J Biol Chem. 1992. PMID: 1527051 Free article.

Structure-function relationship studies of the m3 muscarinic acetylcholine receptor have recently identified a series of threonine and tyrosine residues (all located within the hydrophobic receptor core) that are critically involved in acetylcholine binding (Wess, J …

Structure-function relationship studies of the m3 muscarinic acetylcholine receptor have recently identified a series of threonine and tyros …

3

Site-directed mutagenesis of the m3 muscarinic receptor: identification of a series of threonine and tyrosine residues involved in agonist but not antagonist binding.

Wess J, Gdula D, Brann MR. Wess J, et al. EMBO J. 1991 Dec;10(12):3729-34. doi: 10.1002/j.1460-2075.1991.tb04941.x. EMBO J. 1991. PMID: 1657592 Free PMC article.

4

Muscarinic receptor-operated Ca2+ influx in transfected fibroblast cells is independent of inositol phosphates and release of intracellular Ca2+.

Felder CC, Poulter MO, Wess J. Felder CC, et al. Among authors: wess j. Proc Natl Acad Sci U S A. 1992 Jan 15;89(2):509-13. doi: 10.1073/pnas.89.2.509. Proc Natl Acad Sci U S A. 1992. PMID: 1731321 Free PMC article.

5

Delineation of muscarinic receptor domains conferring selectivity of coupling to guanine nucleotide-binding proteins and second messengers.

Wess J, Bonner TI, Dörje F, Brann MR. Wess J, et al. Mol Pharmacol. 1990 Oct;38(4):517-23. Mol Pharmacol. 1990. PMID: 2172767

6

Chimeric m2/m3 muscarinic receptors: role of carboxyl terminal receptor domains in selectivity of ligand binding and coupling to phosphoinositide hydrolysis.

Wess J, Bonner TI, Brann MR. Wess J, et al. Mol Pharmacol. 1990 Dec;38(6):872-7. Mol Pharmacol. 1990. PMID: 2174507

7

Identification of a small intracellular region of the muscarinic m3 receptor as a determinant of selective coupling to PI turnover.

Wess J, Brann MR, Bonner TI. Wess J, et al. FEBS Lett. 1989 Nov 20;258(1):133-6. doi: 10.1016/0014-5793(89)81633-3. FEBS Lett. 1989. PMID: 2556294 Free article.

8

Plasma membrane localization and functional rescue of truncated forms of a G protein-coupled receptor.

Schöneberg T, Liu J, Wess J. Schöneberg T, et al. Among authors: wess j. J Biol Chem. 1995 Jul 28;270(30):18000-6. doi: 10.1074/jbc.270.30.18000. J Biol Chem. 1995. PMID: 7629108 Free article.

9

Mutational analysis of the relative orientation of transmembrane helices I and VII in G protein-coupled receptors.

Liu J, Schöneberg T, van Rhee M, Wess J. Liu J, et al. Among authors: wess j. J Biol Chem. 1995 Aug 18;270(33):19532-9. doi: 10.1074/jbc.270.33.19532. J Biol Chem. 1995. PMID: 7642637 Free article.

We demonstrated previously that hybrid m2/m5 muscarinic acetylcholine receptors which contain m5 sequence in TM I and m2 sequence in TM VII were unable to bind significant amounts of muscarinic radioligands (Pittel, Z., and Wess, J. (1994) Mol. Pharmacol. 45, 61-64) …

We demonstrated previously that hybrid m2/m5 muscarinic acetylcholine receptors which contain m5 sequence in TM I and m2 sequence in TM VII …

10

Functional role of proline and tryptophan residues highly conserved among G protein-coupled receptors studied by mutational analysis of the m3 muscarinic receptor.

Wess J, Nanavati S, Vogel Z, Maggio R. Wess J, et al. EMBO J. 1993 Jan;12(1):331-8. doi: 10.1002/j.1460-2075.1993.tb05661.x. EMBO J. 1993. PMID: 7679072 Free PMC article.

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