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Synthesis and Evaluation of Fluoroalkyl Phosphonyl Analogues of 2- C-Methylerythritol Phosphate as Substrates and Inhibitors of IspD from Human Pathogens.
J Org Chem. 2018 Sep 7;83(17):9580-9591. doi: 10.1021/acs.joc.8b00686. Epub 2018 Jun 11.
J Org Chem. 2018.
PMID: 29870251
Free PMC article.
Accurate Substrate-Like Probes for Trapping Late-Stage Intermediates in Nonribosomal Peptide Synthetase Condensation Domains.
Wheadon MJ, Townsend CA.
Wheadon MJ, et al.
ACS Chem Biol. 2022 Aug 19;17(8):2046-2053. doi: 10.1021/acschembio.2c00474. Epub 2022 Aug 1.
ACS Chem Biol. 2022.
PMID: 35914245
Free PMC article.
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Evolutionary and functional analysis of an NRPS condensation domain integrates β-lactam, ᴅ-amino acid, and dehydroamino acid synthesis.
Wheadon MJ, Townsend CA.
Wheadon MJ, et al.
Proc Natl Acad Sci U S A. 2021 Apr 27;118(17):e2026017118. doi: 10.1073/pnas.2026017118.
Proc Natl Acad Sci U S A. 2021.
PMID: 33893237
Free PMC article.
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Homeostatic interferon-lambda response to bacterial microbiota stimulates preemptive antiviral defense within discrete pockets of intestinal epithelium.
Van Winkle JA, Peterson ST, Kennedy EA, Wheadon MJ, Ingle H, Desai C, Rodgers R, Constant DA, Wright AP, Li L, Artyomov MN, Lee S, Baldridge MT, Nice TJ.
Van Winkle JA, et al. Among authors: wheadon mj.
Elife. 2022 Feb 9;11:e74072. doi: 10.7554/eLife.74072.
Elife. 2022.
PMID: 35137688
Free PMC article.
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Commensal microbes and interferon-λ determine persistence of enteric murine norovirus infection.
Baldridge MT, Nice TJ, McCune BT, Yokoyama CC, Kambal A, Wheadon M, Diamond MS, Ivanova Y, Artyomov M, Virgin HW.
Baldridge MT, et al.
Science. 2015 Jan 16;347(6219):266-9. doi: 10.1126/science.1258025. Epub 2014 Nov 27.
Science. 2015.
PMID: 25431490
Free PMC article.
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Potent and selective inhibition of SH3 domains with dirhodium metalloinhibitors.
Vohidov F, Knudsen SE, Leonard PG, Ohata J, Wheadon MJ, Popp BV, Ladbury JE, Ball ZT.
Vohidov F, et al. Among authors: wheadon mj.
Chem Sci. 2015 Aug 1;6(8):4778-4783. doi: 10.1039/c5sc01602a. Epub 2015 Jun 3.
Chem Sci. 2015.
PMID: 29142714
Free PMC article.
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