White PW - Search Results

1

Discovery of small-molecule inhibitors of the ATPase activity of human papillomavirus E1 helicase.

Faucher AM, White PW, Brochu C, Grand-Maître C, Rancourt J, Fazal G. Faucher AM, et al. Among authors: white pw. J Med Chem. 2004 Jan 1;47(1):18-21. doi: 10.1021/jm034206x. J Med Chem. 2004. PMID: 14695816

2

Biphenylsulfonacetic acid inhibitors of the human papillomavirus type 6 E1 helicase inhibit ATP hydrolysis by an allosteric mechanism involving tyrosine 486.

White PW, Faucher AM, Massariol MJ, Welchner E, Rancourt J, Cartier M, Archambault J. White PW, et al. Antimicrob Agents Chemother. 2005 Dec;49(12):4834-42. doi: 10.1128/AAC.49.12.4834-4842.2005. Antimicrob Agents Chemother. 2005. PMID: 16304143 Free PMC article.

3

Small molecule inhibitors of the human papillomavirus E1-E2 interaction.

White PW, Faucher AM, Goudreau N. White PW, et al. Curr Top Microbiol Immunol. 2011;348:61-88. doi: 10.1007/82_2010_92. Curr Top Microbiol Immunol. 2011. PMID: 20676971

4

Discovery of the first series of inhibitors of human papillomavirus type 11: inhibition of the assembly of the E1-E2-Origin DNA complex.

Yoakim C, Ogilvie WW, Goudreau N, Naud J, Haché B, O'Meara JA, Cordingley MG, Archambault J, White PW. Yoakim C, et al. Among authors: white pw. Bioorg Med Chem Lett. 2003 Aug 4;13(15):2539-41. doi: 10.1016/s0960-894x(03)00510-9. Bioorg Med Chem Lett. 2003. PMID: 12852961

5

Optimization and determination of the absolute configuration of a series of potent inhibitors of human papillomavirus type-11 E1-E2 protein-protein interaction: a combined medicinal chemistry, NMR and computational chemistry approach.

Goudreau N, Cameron DR, Déziel R, Haché B, Jakalian A, Malenfant E, Naud J, Ogilvie WW, O'meara J, White PW, Yoakim C. Goudreau N, et al. Among authors: white pw. Bioorg Med Chem. 2007 Apr 1;15(7):2690-700. doi: 10.1016/j.bmc.2007.01.036. Epub 2007 Jan 24. Bioorg Med Chem. 2007. PMID: 17306550

6

Inhibition of human papillomavirus DNA replication by small molecule antagonists of the E1-E2 protein interaction.

White PW, Titolo S, Brault K, Thauvette L, Pelletier A, Welchner E, Bourgon L, Doyon L, Ogilvie WW, Yoakim C, Cordingley MG, Archambault J. White PW, et al. J Biol Chem. 2003 Jul 18;278(29):26765-72. doi: 10.1074/jbc.M303608200. Epub 2003 Apr 30. J Biol Chem. 2003. PMID: 12730224 Free article.

7

Discovery of a potent and selective noncovalent linear inhibitor of the hepatitis C virus NS3 protease (BI 201335).

Llinàs-Brunet M, Bailey MD, Goudreau N, Bhardwaj PK, Bordeleau J, Bös M, Bousquet Y, Cordingley MG, Duan J, Forgione P, Garneau M, Ghiro E, Gorys V, Goulet S, Halmos T, Kawai SH, Naud J, Poupart MA, White PW. Llinàs-Brunet M, et al. Among authors: white pw. J Med Chem. 2010 Sep 9;53(17):6466-76. doi: 10.1021/jm100690x. J Med Chem. 2010. PMID: 20715823

8

Evaluation of phosphatidylinositol-4-kinase IIIα as a hepatitis C virus drug target.

Vaillancourt FH, Brault M, Pilote L, Uyttersprot N, Gaillard ET, Stoltz JH, Knight BL, Pantages L, McFarland M, Breitfelder S, Chiu TT, Mahrouche L, Faucher AM, Cartier M, Cordingley MG, Bethell RC, Jiang H, White PW, Kukolj G. Vaillancourt FH, et al. Among authors: white pw. J Virol. 2012 Nov;86(21):11595-607. doi: 10.1128/JVI.01320-12. Epub 2012 Aug 15. J Virol. 2012. PMID: 22896614 Free PMC article.

9

Characterization of the binding site for inhibitors of the HPV11 E1-E2 protein interaction on the E2 transactivation domain by photoaffinity labeling and mass spectrometry.

Davidson W, McGibbon GA, White PW, Yoakim C, Hopkins JL, Guse I, Hambly DM, Frego L, Ogilvie WW, Lavallée P, Archambault J. Davidson W, et al. Among authors: white pw. Anal Chem. 2004 Apr 1;76(7):2095-102. doi: 10.1021/ac035335o. Anal Chem. 2004. PMID: 15053675

10

Characterization of recombinant HPV6 and 11 E1 helicases: effect of ATP on the interaction of E1 with E2 and mapping of a minimal helicase domain.

White PW, Pelletier A, Brault K, Titolo S, Welchner E, Thauvette L, Fazekas M, Cordingley MG, Archambault J. White PW, et al. J Biol Chem. 2001 Jun 22;276(25):22426-38. doi: 10.1074/jbc.M101932200. Epub 2001 Apr 13. J Biol Chem. 2001. PMID: 11304544 Free article.

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