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Page 1
Chemoproteomic Selectivity Profiling of PIKK and PI3K Kinase Inhibitors.
Reinecke M, Ruprecht B, Poser S, Wiechmann S, Wilhelm M, Heinzlmeir S, Kuster B, Médard G. Reinecke M, et al. Among authors: wiechmann s. ACS Chem Biol. 2019 Apr 19;14(4):655-664. doi: 10.1021/acschembio.8b01020. Epub 2019 Apr 3. ACS Chem Biol. 2019. PMID: 30901187
Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion.
Martinelli S, Anderzhanova EA, Bajaj T, Wiechmann S, Dethloff F, Weckmann K, Heinz DE, Ebert T, Hartmann J, Geiger TM, Döngi M, Hafner K, Pöhlmann ML, Jollans L, Philipsen A, Schmidt SV, Schmidt U, Maccarrone G, Stein V, Hausch F, Turck CW, Schmidt MV, Gellner AK, Kuster B, Gassen NC. Martinelli S, et al. Among authors: wiechmann s. Nat Commun. 2021 Jul 30;12(1):4643. doi: 10.1038/s41467-021-24810-5. Nat Commun. 2021. PMID: 34330919 Free PMC article.
Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning.
Stepan J, Heinz DE, Dethloff F, Bajaj T, Zellner A, Hafner K, Wiechmann S, Mackert S, Mecdad Y, Rabenstein M, Ebert T, Martinelli S, Häusl AS, Pöhlmann ML, Hermann A, Ma X, Pavenstädt H, Schmidt MV, Philipsen A, Turck CW, Deussing JM, Kuster B, Wehr MC, Stein V, Kremerskothen J, Wotjak CT, Gassen NC. Stepan J, et al. Among authors: wiechmann s. Cell Rep. 2022 Dec 6;41(10):111766. doi: 10.1016/j.celrep.2022.111766. Cell Rep. 2022. PMID: 36476872 Free article.
Decrypting drug actions and protein modifications by dose- and time-resolved proteomics.
Zecha J, Bayer FP, Wiechmann S, Woortman J, Berner N, Müller J, Schneider A, Kramer K, Abril-Gil M, Hopf T, Reichart L, Chen L, Hansen FM, Lechner S, Samaras P, Eckert S, Lautenbacher L, Reinecke M, Hamood F, Prokofeva P, Vornholz L, Falcomatà C, Dorsch M, Schröder A, Venhuizen A, Wilhelm S, Médard G, Stoehr G, Ruland J, Grüner BM, Saur D, Buchner M, Ruprecht B, Hahne H, The M, Wilhelm M, Kuster B. Zecha J, et al. Among authors: wiechmann s. Science. 2023 Apr 7;380(6640):93-101. doi: 10.1126/science.ade3925. Epub 2023 Mar 16. Science. 2023. PMID: 36926954 Free PMC article.
Inhibiting Hippo pathway kinases releases WWC1 to promote AMPAR-dependent synaptic plasticity and long-term memory in mice.
Stepan J, Heinz DE, Dethloff F, Wiechmann S, Martinelli S, Hafner K, Ebert T, Junglas E, Häusl AS, Pöhlmann ML, Jakovcevski M, Pape JC, Zannas AS, Bajaj T, Hermann A, Ma X, Pavenstädt H, Schmidt MV, Philipsen A, Turck CW, Deussing JM, Rammes G, Robinson AC, Payton A, Wehr MC, Stein V, Murgatroyd C, Kremerskothen J, Kuster B, Wotjak CT, Gassen NC. Stepan J, et al. Among authors: wiechmann s. Sci Signal. 2024 Apr 30;17(834):eadj6603. doi: 10.1126/scisignal.adj6603. Epub 2024 Apr 30. Sci Signal. 2024. PMID: 38687825
30 results