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T cell development critically depends on prethymic stromal patched expression.
Uhmann A, van den Brandt J, Dittmann K, Hess I, Dressel R, Binder C, Lühder F, Christiansen H, Fassnacht M, Bhandoola A, Wienands J, Reichardt HM, Hahn H. Uhmann A, et al. Among authors: wienands j. J Immunol. 2011 Mar 15;186(6):3383-91. doi: 10.4049/jimmunol.1001939. Epub 2011 Feb 11. J Immunol. 2011. PMID: 21317383
The Hedgehog receptor Patched controls lymphoid lineage commitment.
Uhmann A, Dittmann K, Nitzki F, Dressel R, Koleva M, Frommhold A, Zibat A, Binder C, Adham I, Nitsche M, Heller T, Armstrong V, Schulz-Schaeffer W, Wienands J, Hahn H. Uhmann A, et al. Among authors: wienands j. Blood. 2007 Sep 15;110(6):1814-23. doi: 10.1182/blood-2007-02-075648. Epub 2007 May 29. Blood. 2007. PMID: 17536012 Free article.
Ca(2+) signaling in antigen receptor-activated B lymphocytes.
Engelke M, Engels N, Dittmann K, Stork B, Wienands J. Engelke M, et al. Among authors: wienands j. Immunol Rev. 2007 Aug;218:235-46. doi: 10.1111/j.1600-065X.2007.00539.x. Immunol Rev. 2007. PMID: 17624956 Review.
Inactivation of Patched1 in mice leads to development of gastrointestinal stromal-like tumors that express Pdgfrα but not kit.
Pelczar P, Zibat A, van Dop WA, Heijmans J, Bleckmann A, Gruber W, Nitzki F, Uhmann A, Guijarro MV, Hernando E, Dittmann K, Wienands J, Dressel R, Wojnowski L, Binder C, Taguchi T, Beissbarth T, Hogendoorn PC, Antonescu CR, Rubin BP, Schulz-Schaeffer W, Aberger F, van den Brink GR, Hahn H. Pelczar P, et al. Among authors: wienands j. Gastroenterology. 2013 Jan;144(1):134-144.e6. doi: 10.1053/j.gastro.2012.09.061. Epub 2012 Oct 3. Gastroenterology. 2013. PMID: 23041331 Free PMC article.
The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain.
Schneppenheim J, Dressel R, Hüttl S, Lüllmann-Rauch R, Engelke M, Dittmann K, Wienands J, Eskelinen EL, Hermans-Borgmeyer I, Fluhrer R, Saftig P, Schröder B. Schneppenheim J, et al. Among authors: wienands j. J Exp Med. 2013 Jan 14;210(1):41-58. doi: 10.1084/jem.20121069. Epub 2012 Dec 24. J Exp Med. 2013. PMID: 23267015 Free PMC article.
PI3K inhibition enhances doxorubicin-induced apoptosis in sarcoma cells.
Marklein D, Graab U, Naumann I, Yan T, Ridzewski R, Nitzki F, Rosenberger A, Dittmann K, Wienands J, Wojnowski L, Fulda S, Hahn H. Marklein D, et al. Among authors: wienands j. PLoS One. 2012;7(12):e52898. doi: 10.1371/journal.pone.0052898. Epub 2012 Dec 31. PLoS One. 2012. PMID: 23300809 Free PMC article.
112 results