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Heparan sulfate-dependent ERK activation contributes to the overexpression of fibrotic proteins and enhanced contraction by scleroderma fibroblasts.
Chen Y, Leask A, Abraham DJ, Pala D, Shiwen X, Khan K, Liu S, Carter DE, Wilcox-Adelman S, Goetinck P, Denton CP, Black CM, Pitsillides AA, Sarraf CE, Eastwood M. Chen Y, et al. Among authors: wilcox adelman s. Arthritis Rheum. 2008 Feb;58(2):577-85. doi: 10.1002/art.23146. Arthritis Rheum. 2008. PMID: 18240216 Free article.
Matrix contraction by dermal fibroblasts requires transforming growth factor-beta/activin-linked kinase 5, heparan sulfate-containing proteoglycans, and MEK/ERK: insights into pathological scarring in chronic fibrotic disease.
Chen Y, Shi-Wen X, van Beek J, Kennedy L, McLeod M, Renzoni EA, Bou-Gharios G, Wilcox-Adelman S, Goetinck PF, Eastwood M, Black CM, Abraham DJ, Leask A. Chen Y, et al. Among authors: wilcox adelman s. Am J Pathol. 2005 Dec;167(6):1699-711. doi: 10.1016/s0002-9440(10)61252-7. Am J Pathol. 2005. PMID: 16314481 Free PMC article.
Syndecan-4 modulates focal adhesion kinase phosphorylation.
Wilcox-Adelman SA, Denhez F, Goetinck PF. Wilcox-Adelman SA, et al. J Biol Chem. 2002 Sep 6;277(36):32970-7. doi: 10.1074/jbc.M201283200. Epub 2002 Jun 26. J Biol Chem. 2002. PMID: 12087088 Free article.
Syndecan-4: dispensable or indispensable?
Wilcox-Adelman SA, Denhez F, Iwabuchi T, Saoncella S, Calautti E, Goetinck PF. Wilcox-Adelman SA, et al. Glycoconj J. 2002 May-Jun;19(4-5):305-13. doi: 10.1023/A:1025304602057. Glycoconj J. 2002. PMID: 12975609 Review.
Syndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathway.
Finsen AV, Lunde IG, Sjaastad I, Østli EK, Lyngra M, Jarstadmarken HO, Hasic A, Nygård S, Wilcox-Adelman SA, Goetinck PF, Lyberg T, Skrbic B, Florholmen G, Tønnessen T, Louch WE, Djurovic S, Carlson CR, Christensen G. Finsen AV, et al. Among authors: wilcox adelman sa. PLoS One. 2011;6(12):e28302. doi: 10.1371/journal.pone.0028302. Epub 2011 Dec 2. PLoS One. 2011. PMID: 22164265 Free PMC article.
15 results