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Rescue of progranulin deficiency associated with frontotemporal lobar degeneration by alkalizing reagents and inhibition of vacuolar ATPase.
Capell A, Liebscher S, Fellerer K, Brouwers N, Willem M, Lammich S, Gijselinck I, Bittner T, Carlson AM, Sasse F, Kunze B, Steinmetz H, Jansen R, Dormann D, Sleegers K, Cruts M, Herms J, Van Broeckhoven C, Haass C. Capell A, et al. Among authors: willem m. J Neurosci. 2011 Feb 2;31(5):1885-94. doi: 10.1523/JNEUROSCI.5757-10.2011. J Neurosci. 2011. PMID: 21289198 Free PMC article.
Maturation and pro-peptide cleavage of beta-secretase.
Capell A, Steiner H, Willem M, Kaiser H, Meyer C, Walter J, Lammich S, Multhaup G, Haass C. Capell A, et al. Among authors: willem m. J Biol Chem. 2000 Oct 6;275(40):30849-54. doi: 10.1074/jbc.M003202200. J Biol Chem. 2000. PMID: 10801872 Free article.
Phosphorylation regulates intracellular trafficking of beta-secretase.
Walter J, Fluhrer R, Hartung B, Willem M, Kaether C, Capell A, Lammich S, Multhaup G, Haass C. Walter J, et al. Among authors: willem m. J Biol Chem. 2001 May 4;276(18):14634-41. doi: 10.1074/jbc.M011116200. Epub 2001 Jan 29. J Biol Chem. 2001. PMID: 11278841 Free article.
A non-amyloidogenic function of BACE-2 in the secretory pathway.
Fluhrer R, Capell A, Westmeyer G, Willem M, Hartung B, Condron MM, Teplow DB, Haass C, Walter J. Fluhrer R, et al. Among authors: willem m. J Neurochem. 2002 Jun;81(5):1011-20. doi: 10.1046/j.1471-4159.2002.00908.x. J Neurochem. 2002. PMID: 12065613 Free article.
Control of peripheral nerve myelination by the beta-secretase BACE1.
Willem M, Garratt AN, Novak B, Citron M, Kaufmann S, Rittger A, DeStrooper B, Saftig P, Birchmeier C, Haass C. Willem M, et al. Science. 2006 Oct 27;314(5799):664-6. doi: 10.1126/science.1132341. Epub 2006 Sep 21. Science. 2006. PMID: 16990514
75 results