Williamson RA - Search Results

1

Characterisation of complex formation between members of the Mycobacterium tuberculosis complex CFP-10/ESAT-6 protein family: towards an understanding of the rules governing complex formation and thereby functional flexibility.

Lightbody KL, Renshaw PS, Collins ML, Wright RL, Hunt DM, Gordon SV, Hewinson RG, Buxton RS, Williamson RA, Carr MD. Lightbody KL, et al. Among authors: williamson ra. FEMS Microbiol Lett. 2004 Sep 1;238(1):255-62. doi: 10.1016/j.femsle.2004.07.043. FEMS Microbiol Lett. 2004. PMID: 15336430

2

Conclusive evidence that the major T-cell antigens of the Mycobacterium tuberculosis complex ESAT-6 and CFP-10 form a tight, 1:1 complex and characterization of the structural properties of ESAT-6, CFP-10, and the ESAT-6*CFP-10 complex. Implications for pathogenesis and virulence.

Renshaw PS, Panagiotidou P, Whelan A, Gordon SV, Hewinson RG, Williamson RA, Carr MD. Renshaw PS, et al. Among authors: williamson ra. J Biol Chem. 2002 Jun 14;277(24):21598-603. doi: 10.1074/jbc.M201625200. Epub 2002 Apr 8. J Biol Chem. 2002. PMID: 11940590 Free article.

3

Solution structure of the Mycobacterium tuberculosis complex protein MPB70: from tuberculosis pathogenesis to inherited human corneal desease.

Carr MD, Bloemink MJ, Dentten E, Whelan AO, Gordon SV, Kelly G, Frenkiel TA, Hewinson RG, Williamson RA. Carr MD, et al. Among authors: williamson ra. J Biol Chem. 2003 Oct 31;278(44):43736-43. doi: 10.1074/jbc.M307235200. Epub 2003 Aug 12. J Biol Chem. 2003. PMID: 12917404 Free article.

4

Structure and function of the complex formed by the tuberculosis virulence factors CFP-10 and ESAT-6.

Renshaw PS, Lightbody KL, Veverka V, Muskett FW, Kelly G, Frenkiel TA, Gordon SV, Hewinson RG, Burke B, Norman J, Williamson RA, Carr MD. Renshaw PS, et al. Among authors: williamson ra. EMBO J. 2005 Jul 20;24(14):2491-8. doi: 10.1038/sj.emboj.7600732. Epub 2005 Jun 23. EMBO J. 2005. PMID: 15973432 Free PMC article.

5

Molecular features governing the stability and specificity of functional complex formation by Mycobacterium tuberculosis CFP-10/ESAT-6 family proteins.

Lightbody KL, Ilghari D, Waters LC, Carey G, Bailey MA, Williamson RA, Renshaw PS, Carr MD. Lightbody KL, et al. Among authors: williamson ra. J Biol Chem. 2008 Jun 20;283(25):17681-90. doi: 10.1074/jbc.M800123200. Epub 2008 Apr 21. J Biol Chem. 2008. PMID: 18430736 Free article.

6

Sequence-specific assignment and secondary structure determination of the 195-residue complex formed by the Mycobacterium tuberculosis proteins CFP-10 and ESAT-6.

Renshaw PS, Veverka V, Kelly G, Frenkiel TA, Williamson RA, Gordon SV, Hewinson RG, Carr MD. Renshaw PS, et al. Among authors: williamson ra. J Biomol NMR. 2004 Oct;30(2):225-6. doi: 10.1023/B:JNMR.0000048852.40853.5c. J Biomol NMR. 2004. PMID: 15557808 No abstract available.

7

The effect of matrix metalloproteinase complex formation on the conformational mobility of tissue inhibitor of metalloproteinases-2 (TIMP-2).

Williamson RA, Muskett FW, Howard MJ, Freedman RB, Carr MD. Williamson RA, et al. J Biol Chem. 1999 Dec 24;274(52):37226-32. doi: 10.1074/jbc.274.52.37226. J Biol Chem. 1999. PMID: 10601286 Free article.

8

Sequence-specific assignment of the B-Myb DNA-binding domain (B-MybR2R3) bound to a 16 base-pair DNA target site corresponding to a regulatory site from the tom-1 gene.

Jones G, Howard M, McIntosh P, Williamson RA, Carr MD. Jones G, et al. Among authors: williamson ra. J Biomol NMR. 2003 Aug;26(4):375-6. doi: 10.1023/a:1024005124375. J Biomol NMR. 2003. PMID: 12815265 No abstract available.

9

Mapping the binding site for matrix metalloproteinase on the N-terminal domain of the tissue inhibitor of metalloproteinases-2 by NMR chemical shift perturbation.

Williamson RA, Carr MD, Frenkiel TA, Feeney J, Freedman RB. Williamson RA, et al. Biochemistry. 1997 Nov 11;36(45):13882-9. doi: 10.1021/bi9712091. Biochemistry. 1997. PMID: 9374866

10

Sequence-specific assignment and determination of the secondary structure of the 163-residue M. tuberculosis and M. bovis antigenic protein mpb70.

Bloemink MJ, Kemmink J, Dentten E, Muskett FW, Whelan A, Sheikh A, Hewinson G, Williamson RA, Carr MD. Bloemink MJ, et al. Among authors: williamson ra. J Biomol NMR. 2001 Jun;20(2):185-6. doi: 10.1023/a:1011239727839. J Biomol NMR. 2001. PMID: 11495252 No abstract available.

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