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Genetic stability of genome-scale deoptimized RNA virus vaccine candidates under selective pressure.
Le Nouën C, McCarty T, Brown M, Smith ML, Lleras R, Dolan MA, Mehedi M, Yang L, Luongo C, Liang B, Munir S, DiNapoli JM, Mueller S, Wimmer E, Collins PL, Buchholz UJ. Le Nouën C, et al. Among authors: wimmer e. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E386-E395. doi: 10.1073/pnas.1619242114. Epub 2017 Jan 3. Proc Natl Acad Sci U S A. 2017. PMID: 28049853 Free PMC article.
Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization.
Le Nouën C, Brock LG, Luongo C, McCarty T, Yang L, Mehedi M, Wimmer E, Mueller S, Collins PL, Buchholz UJ, DiNapoli JM. Le Nouën C, et al. Among authors: wimmer e. Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13169-74. doi: 10.1073/pnas.1411290111. Epub 2014 Aug 25. Proc Natl Acad Sci U S A. 2014. PMID: 25157129 Free PMC article.
Virus attenuation by genome-scale changes in codon pair bias.
Coleman JR, Papamichail D, Skiena S, Futcher B, Wimmer E, Mueller S. Coleman JR, et al. Among authors: wimmer e. Science. 2008 Jun 27;320(5884):1784-7. doi: 10.1126/science.1155761. Science. 2008. PMID: 18583614 Free PMC article.
485 results