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Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3.
Boyd S, Brookfield JL, Critchlow SE, Cumming IA, Curtis NJ, Debreczeni J, Degorce SL, Donald C, Evans NJ, Groombridge S, Hopcroft P, Jones NP, Kettle JG, Lamont S, Lewis HJ, MacFaull P, McLoughlin SB, Rigoreau LJ, Smith JM, St-Gallay S, Stock JK, Turnbull AP, Wheatley ER, Winter J, Wingfield J. Boyd S, et al. Among authors: wingfield j. J Med Chem. 2015 Apr 23;58(8):3611-25. doi: 10.1021/acs.jmedchem.5b00352. Epub 2015 Apr 13. J Med Chem. 2015. PMID: 25849762
Design and synthesis of novel lactate dehydrogenase A inhibitors by fragment-based lead generation.
Ward RA, Brassington C, Breeze AL, Caputo A, Critchlow S, Davies G, Goodwin L, Hassall G, Greenwood R, Holdgate GA, Mrosek M, Norman RA, Pearson S, Tart J, Tucker JA, Vogtherr M, Whittaker D, Wingfield J, Winter J, Hudson K. Ward RA, et al. Among authors: wingfield j. J Med Chem. 2012 Apr 12;55(7):3285-306. doi: 10.1021/jm201734r. Epub 2012 Mar 26. J Med Chem. 2012. PMID: 22417091
Acoustic Mist Ionization Platform for Direct and Contactless Ultrahigh-Throughput Mass Spectrometry Analysis of Liquid Samples.
Sinclair I, Bachman M, Addison D, Rohman M, Murray DC, Davies G, Mouchet E, Tonge ME, Stearns RG, Ghislain L, Datwani SS, Majlof L, Hall E, Jones GR, Hoyes E, Olechno J, Ellson RN, Barran PE, Pringle SD, Morris MR, Wingfield J. Sinclair I, et al. Among authors: wingfield j. Anal Chem. 2019 Mar 19;91(6):3790-3794. doi: 10.1021/acs.analchem.9b00142. Epub 2019 Mar 11. Anal Chem. 2019. PMID: 30835099
Advances in Mass Spectrometry Within Drug Discovery.
Wingfield J, Wilson ID. Wingfield J, et al. J Biomol Screen. 2016 Feb;21(2):109-10. doi: 10.1177/1087057115623454. J Biomol Screen. 2016. PMID: 26773070 No abstract available.
399 results