Winklhofer KF - Search Results

1

Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system.

Brychzy A, Rein T, Winklhofer KF, Hartl FU, Young JC, Obermann WM. Brychzy A, et al. Among authors: winklhofer kf. EMBO J. 2003 Jul 15;22(14):3613-23. doi: 10.1093/emboj/cdg362. EMBO J. 2003. PMID: 12853476 Free PMC article.

2

A sensitive filter retention assay for the detection of PrP(Sc) and the screening of anti-prion compounds.

Winklhofer KF, Hartl FU, Tatzelt J. Winklhofer KF, et al. FEBS Lett. 2001 Aug 10;503(1):41-5. doi: 10.1016/s0014-5793(01)02692-8. FEBS Lett. 2001. PMID: 11513851 Free article.

3

Inactivation of parkin by oxidative stress and C-terminal truncations: a protective role of molecular chaperones.

Winklhofer KF, Henn IH, Kay-Jackson PC, Heller U, Tatzelt J. Winklhofer KF, et al. J Biol Chem. 2003 Nov 21;278(47):47199-208. doi: 10.1074/jbc.M306769200. Epub 2003 Sep 12. J Biol Chem. 2003. PMID: 12972428 Free article.

4

Systematic identification of antiprion drugs by high-throughput screening based on scanning for intensely fluorescent targets.

Bertsch U, Winklhofer KF, Hirschberger T, Bieschke J, Weber P, Hartl FU, Tavan P, Tatzelt J, Kretzschmar HA, Giese A. Bertsch U, et al. Among authors: winklhofer kf. J Virol. 2005 Jun;79(12):7785-91. doi: 10.1128/JVI.79.12.7785-7791.2005. J Virol. 2005. PMID: 15919931 Free PMC article.

5

The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication.

Resenberger UK, Harmeier A, Woerner AC, Goodman JL, Müller V, Krishnan R, Vabulas RM, Kretzschmar HA, Lindquist S, Hartl FU, Multhaup G, Winklhofer KF, Tatzelt J. Resenberger UK, et al. Among authors: winklhofer kf. EMBO J. 2011 May 18;30(10):2057-70. doi: 10.1038/emboj.2011.86. Epub 2011 Mar 25. EMBO J. 2011. PMID: 21441896 Free PMC article.

6

Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants.

Klein P, Müller-Rischart AK, Motori E, Schönbauer C, Schnorrer F, Winklhofer KF, Klein R. Klein P, et al. Among authors: winklhofer kf. EMBO J. 2014 Feb 18;33(4):341-55. doi: 10.1002/embj.201284290. Epub 2014 Jan 28. EMBO J. 2014. PMID: 24473149 Free PMC article.

7

Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA.

Woerner AC, Frottin F, Hornburg D, Feng LR, Meissner F, Patra M, Tatzelt J, Mann M, Winklhofer KF, Hartl FU, Hipp MS. Woerner AC, et al. Among authors: winklhofer kf. Science. 2016 Jan 8;351(6269):173-6. doi: 10.1126/science.aad2033. Epub 2015 Dec 3. Science. 2016. PMID: 26634439

8

A protein quality control pathway regulated by linear ubiquitination.

van Well EM, Bader V, Patra M, Sánchez-Vicente A, Meschede J, Furthmann N, Schnack C, Blusch A, Longworth J, Petrasch-Parwez E, Mori K, Arzberger T, Trümbach D, Angersbach L, Showkat C, Sehr DA, Berlemann LA, Goldmann P, Clement AM, Behl C, Woerner AC, Saft C, Wurst W, Haass C, Ellrichmann G, Gold R, Dittmar G, Hipp MS, Hartl FU, Tatzelt J, Winklhofer KF. van Well EM, et al. Among authors: winklhofer kf. EMBO J. 2019 May 2;38(9):e100730. doi: 10.15252/embj.2018100730. Epub 2019 Mar 18. EMBO J. 2019. PMID: 30886048 Free PMC article.

9

Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease.

Gilch S, Winklhofer KF, Groschup MH, Nunziante M, Lucassen R, Spielhaupter C, Muranyi W, Riesner D, Tatzelt J, Schätzl HM. Gilch S, et al. Among authors: winklhofer kf. EMBO J. 2001 Aug 1;20(15):3957-66. doi: 10.1093/emboj/20.15.3957. EMBO J. 2001. PMID: 11483499 Free PMC article.

10

Geldanamycin restores a defective heat shock response in vivo.

Winklhofer KF, Reintjes A, Hoener MC, Voellmy R, Tatzelt J. Winklhofer KF, et al. J Biol Chem. 2001 Nov 30;276(48):45160-7. doi: 10.1074/jbc.M104873200. Epub 2001 Sep 26. J Biol Chem. 2001. PMID: 11574536 Free article.

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