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Apc-mutant cells act as supercompetitors in intestinal tumour initiation.
van Neerven SM, de Groot NE, Nijman LE, Scicluna BP, van Driel MS, Lecca MC, Warmerdam DO, Kakkar V, Moreno LF, Vieira Braga FA, Sanches DR, Ramesh P, Ten Hoorn S, Aelvoet AS, van Boxel MF, Koens L, Krawczyk PM, Koster J, Dekker E, Medema JP, Winton DJ, Bijlsma MF, Morrissey E, Léveillé N, Vermeulen L. van Neerven SM, et al. Among authors: winton dj. Nature. 2021 Jun;594(7863):436-441. doi: 10.1038/s41586-021-03558-4. Epub 2021 Jun 2. Nature. 2021. PMID: 34079128
Defining stem cell dynamics in models of intestinal tumor initiation.
Vermeulen L, Morrissey E, van der Heijden M, Nicholson AM, Sottoriva A, Buczacki S, Kemp R, Tavaré S, Winton DJ. Vermeulen L, et al. Among authors: winton dj. Science. 2013 Nov 22;342(6161):995-8. doi: 10.1126/science.1243148. Science. 2013. PMID: 24264992
Bcl-2 is a critical mediator of intestinal transformation.
van der Heijden M, Zimberlin CD, Nicholson AM, Colak S, Kemp R, Meijer SL, Medema JP, Greten FR, Jansen M, Winton DJ, Vermeulen L. van der Heijden M, et al. Among authors: winton dj. Nat Commun. 2016 Mar 9;7:10916. doi: 10.1038/ncomms10916. Nat Commun. 2016. PMID: 26956214 Free PMC article.
Turning off the BCL-2 switch to prevent intestinal tumorigenesis.
van der Heijden M, Winton DJ, Vermeulen L. van der Heijden M, et al. Among authors: winton dj. Oncotarget. 2016 May 17;7(20):28763-4. doi: 10.18632/oncotarget.8757. Oncotarget. 2016. PMID: 27095579 Free PMC article. No abstract available.
Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells.
Huels DJ, Bruens L, Hodder MC, Cammareri P, Campbell AD, Ridgway RA, Gay DM, Solar-Abboud M, Faller WJ, Nixon C, Zeiger LB, McLaughlin ME, Morrissey E, Winton DJ, Snippert HJ, van Rheenen J, Sansom OJ. Huels DJ, et al. Among authors: winton dj. Nat Commun. 2018 Mar 19;9(1):1132. doi: 10.1038/s41467-018-03426-2. Nat Commun. 2018. PMID: 29556067 Free PMC article.
Itraconazole targets cell cycle heterogeneity in colorectal cancer.
Buczacki SJA, Popova S, Biggs E, Koukorava C, Buzzelli J, Vermeulen L, Hazelwood L, Francies H, Garnett MJ, Winton DJ. Buczacki SJA, et al. Among authors: winton dj. J Exp Med. 2018 Jul 2;215(7):1891-1912. doi: 10.1084/jem.20171385. Epub 2018 May 31. J Exp Med. 2018. PMID: 29853607 Free PMC article.
91 results