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Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes.
Baxter M, Withey S, Harrison S, Segeritz CP, Zhang F, Atkinson-Dell R, Rowe C, Gerrard DT, Sison-Young R, Jenkins R, Henry J, Berry AA, Mohamet L, Best M, Fenwick SW, Malik H, Kitteringham NR, Goldring CE, Piper Hanley K, Vallier L, Hanley NA. Baxter M, et al. Among authors: withey s. J Hepatol. 2015 Mar;62(3):581-9. doi: 10.1016/j.jhep.2014.10.016. Epub 2014 Oct 18. J Hepatol. 2015. PMID: 25457200 Free PMC article.
Laser Capture and Deep Sequencing Reveals the Transcriptomic Programmes Regulating the Onset of Pancreas and Liver Differentiation in Human Embryos.
Jennings RE, Berry AA, Gerrard DT, Wearne SJ, Strutt J, Withey S, Chhatriwala M, Piper Hanley K, Vallier L, Bobola N, Hanley NA. Jennings RE, et al. Among authors: withey s. Stem Cell Reports. 2017 Nov 14;9(5):1387-1394. doi: 10.1016/j.stemcr.2017.09.018. Epub 2017 Oct 19. Stem Cell Reports. 2017. PMID: 29056335 Free PMC article.
Dynamic changes in the epigenomic landscape regulate human organogenesis and link to developmental disorders.
Gerrard DT, Berry AA, Jennings RE, Birket MJ, Zarrineh P, Garstang MG, Withey SL, Short P, Jiménez-Gancedo S, Firbas PN, Donaldson I, Sharrocks AD, Hanley KP, Hurles ME, Gomez-Skarmeta JL, Bobola N, Hanley NA. Gerrard DT, et al. Among authors: withey sl. Nat Commun. 2020 Aug 6;11(1):3920. doi: 10.1038/s41467-020-17305-2. Nat Commun. 2020. PMID: 32764605 Free PMC article.
Impaired endoplasmic reticulum-mitochondrial signaling in ataxia-telangiectasia.
Yeo AJ, Chong KL, Gatei M, Zou D, Stewart R, Withey S, Wolvetang E, Parton RG, Brown AD, Kastan MB, Coman D, Lavin MF. Yeo AJ, et al. Among authors: withey s. iScience. 2020 Dec 23;24(1):101972. doi: 10.1016/j.isci.2020.101972. eCollection 2021 Jan 22. iScience. 2020. PMID: 33437944 Free PMC article.
117 results