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The full spectrum of SLC22 OCT1 mutations illuminates the bridge between drug transporter biophysics and pharmacogenomics.
Yee SW, Macdonald CB, Mitrovic D, Zhou X, Koleske ML, Yang J, Buitrago Silva D, Rockefeller Grimes P, Trinidad DD, More SS, Kachuri L, Witte JS, Delemotte L, Giacomini KM, Coyote-Maestas W. Yee SW, et al. Among authors: witte js. Mol Cell. 2024 May 2:S1097-2765(24)00323-X. doi: 10.1016/j.molcel.2024.04.008. Online ahead of print. Mol Cell. 2024. PMID: 38703769
Increased β2-adrenergic signaling promotes fracture healing through callus neovascularization in mice.
Jahn D, Knapstein PR, Otto E, Köhli P, Sevecke J, Graef F, Graffmann C, Fuchs M, Jiang S, Rickert M, Erdmann C, Appelt J, Revend L, Küttner Q, Witte J, Rahmani A, Duda G, Xie W, Donat A, Schinke T, Ivanov A, Tchouto MN, Beule D, Frosch KH, Baranowsky A, Tsitsilonis S, Keller J. Jahn D, et al. Among authors: witte j. Sci Transl Med. 2024 Apr 17;16(743):eadk9129. doi: 10.1126/scitranslmed.adk9129. Epub 2024 Apr 17. Sci Transl Med. 2024. PMID: 38630849
A longitudinal causal graph analysis investigating modifiable risk factors and obesity in a European cohort of children and adolescents.
Foraita R, Witte J, Börnhorst C, Gwozdz W, Pala V, Lissner L, Lauria F, Reisch LA, Molnár D, De Henauw S, Moreno L, Veidebaum T, Tornaritis M, Pigeot I, Didelez V. Foraita R, et al. Among authors: witte j. Sci Rep. 2024 Mar 21;14(1):6822. doi: 10.1038/s41598-024-56721-y. Sci Rep. 2024. PMID: 38514750 Free PMC article.
Admix-kit: an integrated toolkit and pipeline for genetic analyses of admixed populations.
Hou K, Gogarten S, Kim J, Hua X, Dias JA, Sun Q, Wang Y, Tan T; Polygenic Risk Methods in Diverse Populations (PRIMED) Consortium Methods Working Group; Atkinson EG, Martin A, Shortt J, Hirbo J, Li Y, Pasaniuc B, Zhang H. Hou K, et al. Bioinformatics. 2024 Mar 29;40(4):btae148. doi: 10.1093/bioinformatics/btae148. Bioinformatics. 2024. PMID: 38490256 Free PMC article.
Contact allergies to dental materials in patients.
Forkel S, Schubert S, Corvin L, Heine G, Lang CCV, Oppel E, Pföhler C, Treudler R, Bauer A, Sulk M, Kränke B, Schäkel K, Heratizadeh A, Worm M, Witte J, Geier J, Buhl T. Forkel S, et al. Among authors: witte j. Br J Dermatol. 2023 Dec 20:ljad525. doi: 10.1093/bjd/ljad525. Online ahead of print. Br J Dermatol. 2023. PMID: 38123140
Implementing integrated care guidelines in asthma and COPD: It ain't easy!
Witte JA, Birnie E, Braunstahl GJ, van den Akker E, van Litsenburg WJM, Chavannes NH, Rutten-van Mölken MPMH, In 't Veen JCCM. Witte JA, et al. Heliyon. 2023 Oct 31;9(11):e21540. doi: 10.1016/j.heliyon.2023.e21540. eCollection 2023 Nov. Heliyon. 2023. PMID: 38027862 Free PMC article.
Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves cross-ancestry prediction.
Hoffmann TJ, Graff RE, Madduri RK, Rodriguez AA, Cario CL, Feng K, Jiang Y, Wang A, Klein RJ, Pierce BL, Eggener S, Tong L, Blot W, Long J, Rebbeck T, Lachance J, Andrews C, Adebiyi AO, Adusei B, Aisuodionoe-Shadrach OI, Fernandez PW, Jalloh M, Janivara R, Chen WC, Mensah JE, Agalliu I, Berndt SI, Shelley JP, Schaffer K, Machiela MJ, Freedman ND, Huang WY, Li SA, Goodman PJ, Till C, Thompson I, Lilja H, Van Den Eeden SK, Chanock SJ, Mosley JD, Conti DV, Haiman CA, Justice AC, Kachuri L, Witte JS. Hoffmann TJ, et al. Among authors: witte js. medRxiv [Preprint]. 2023 Oct 30:2023.10.27.23297676. doi: 10.1101/2023.10.27.23297676. medRxiv. 2023. PMID: 37961155 Free PMC article. Preprint.
765 results