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Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions.
Napoli C, D'Armiento FP, Mancini FP, Postiglione A, Witztum JL, Palumbo G, Palinski W. Napoli C, et al. Among authors: witztum jl. J Clin Invest. 1997 Dec 1;100(11):2680-90. doi: 10.1172/JCI119813. J Clin Invest. 1997. PMID: 9389731 Free PMC article.
Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids. Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein.
Hörkkö S, Miller E, Dudl E, Reaven P, Curtiss LK, Zvaifler NJ, Terkeltaub R, Pierangeli SS, Branch DW, Palinski W, Witztum JL. Hörkkö S, et al. Among authors: witztum jl. J Clin Invest. 1996 Aug 1;98(3):815-25. doi: 10.1172/JCI118854. J Clin Invest. 1996. PMID: 8698874 Free PMC article.
Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins.
Hörkkö S, Bird DA, Miller E, Itabe H, Leitinger N, Subbanagounder G, Berliner JA, Friedman P, Dennis EA, Curtiss LK, Palinski W, Witztum JL. Hörkkö S, et al. Among authors: witztum jl. J Clin Invest. 1999 Jan;103(1):117-28. doi: 10.1172/JCI4533. J Clin Invest. 1999. PMID: 9884341 Free PMC article.
477 results