Woerle HJ - Search Results

1

Pharmacodynamic Effects of Single and Multiple Doses of Empagliflozin in Patients With Type 2 Diabetes.

Heise T, Jordan J, Wanner C, Heer M, Macha S, Mattheus M, Lund SS, Woerle HJ, Broedl UC. Heise T, et al. Among authors: woerle hj. Clin Ther. 2016 Oct;38(10):2265-2276. doi: 10.1016/j.clinthera.2016.09.001. Epub 2016 Sep 28. Clin Ther. 2016. PMID: 27692976 Clinical Trial.

2

Pharmacokinetics of empagliflozin, a sodium glucose cotransporter-2 (SGLT-2) inhibitor, coadministered with sitagliptin in healthy volunteers.

Brand T, Macha S, Mattheus M, Pinnetti S, Woerle HJ. Brand T, et al. Among authors: woerle hj. Adv Ther. 2012 Oct;29(10):889-99. doi: 10.1007/s12325-012-0055-3. Epub 2012 Oct 1. Adv Ther. 2012. PMID: 23054692 Clinical Trial.

3

Pharmacokinetics of empagliflozin, a sodium glucose cotransporter-2 (SGLT2) inhibitor, and metformin following co-administration in healthy volunteers.

Macha S, Dieterich S, Mattheus M, Seman LJ, Broedl UC, Woerle HJ. Macha S, et al. Among authors: woerle hj. Int J Clin Pharmacol Ther. 2013 Feb;51(2):132-40. doi: 10.5414/CP201794. Int J Clin Pharmacol Ther. 2013. PMID: 23253948 Clinical Trial.

4

A randomized, open-label, crossover study to evaluate the pharmacokinetics of empagliflozin and linagliptin after coadministration in healthy male volunteers.

Friedrich C, Metzmann K, Rose P, Mattheus M, Pinnetti S, Woerle HJ. Friedrich C, et al. Among authors: woerle hj. Clin Ther. 2013 Jan;35(1):A33-42. doi: 10.1016/j.clinthera.2012.12.002. Clin Ther. 2013. PMID: 23328275 Clinical Trial.

5

Lack of clinically relevant drug-drug interaction between empagliflozin, a sodium glucose cotransporter 2 inhibitor, and verapamil, ramipril, or digoxin in healthy volunteers.

Macha S, Sennewald R, Rose P, Schoene K, Pinnetti S, Woerle HJ, Broedl UC. Macha S, et al. Among authors: woerle hj. Clin Ther. 2013 Mar;35(3):226-35. doi: 10.1016/j.clinthera.2013.02.015. Clin Ther. 2013. PMID: 23497760 Clinical Trial.

6

Effect of empagliflozin on the steady-state pharmacokinetics of ethinylestradiol and levonorgestrel in healthy female volunteers.

Macha S, Mattheus M, Pinnetti S, Woerle HJ, Broedl UC. Macha S, et al. Among authors: woerle hj. Clin Drug Investig. 2013 May;33(5):351-7. doi: 10.1007/s40261-013-0068-y. Clin Drug Investig. 2013. PMID: 23512637 Clinical Trial.

7

Effect of food on the pharmacokinetics of empagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, and assessment of dose proportionality in healthy volunteers.

Macha S, Jungnik A, Hohl K, Hobson D, Salsali A, Woerle HJ. Macha S, et al. Among authors: woerle hj. Int J Clin Pharmacol Ther. 2013 Nov;51(11):873-9. doi: 10.5414/cp201948. Int J Clin Pharmacol Ther. 2013. PMID: 24152604 Clinical Trial.

8

Effect of gemfibrozil, rifampicin, or probenecid on the pharmacokinetics of the SGLT2 inhibitor empagliflozin in healthy volunteers.

Macha S, Koenen R, Sennewald R, Schöne K, Hummel N, Riedmaier S, Woerle HJ, Salsali A, Broedl UC. Macha S, et al. Among authors: woerle hj. Clin Ther. 2014 Feb 1;36(2):280-90.e1. doi: 10.1016/j.clinthera.2014.01.003. Epub 2014 Feb 1. Clin Ther. 2014. PMID: 24491572 Clinical Trial.

9

Empagliflozin as add-on to metformin in patients with type 2 diabetes: a 24-week, randomized, double-blind, placebo-controlled trial.

Häring HU, Merker L, Seewaldt-Becker E, Weimer M, Meinicke T, Broedl UC, Woerle HJ; EMPA-REG MET Trial Investigators. Häring HU, et al. Among authors: woerle hj. Diabetes Care. 2014 Jun;37(6):1650-9. doi: 10.2337/dc13-2105. Epub 2014 Apr 10. Diabetes Care. 2014. PMID: 24722494 Clinical Trial.

10

Improved glucose control with weight loss, lower insulin doses, and no increased hypoglycemia with empagliflozin added to titrated multiple daily injections of insulin in obese inadequately controlled type 2 diabetes.

Rosenstock J, Jelaska A, Frappin G, Salsali A, Kim G, Woerle HJ, Broedl UC; EMPA-REG MDI Trial Investigators. Rosenstock J, et al. Among authors: woerle hj. Diabetes Care. 2014 Jul;37(7):1815-23. doi: 10.2337/dc13-3055. Epub 2014 Jun 14. Diabetes Care. 2014. PMID: 24929430 Clinical Trial.

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