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Effect of selective BET protein inhibitor apabetalone on cardiovascular outcomes in patients with acute coronary syndrome and diabetes: Rationale, design, and baseline characteristics of the BETonMACE trial.
Ray KK, Nicholls SJ, Ginsberg HD, Johansson JO, Kalantar-Zadeh K, Kulikowski E, Toth PP, Wong N, Cummings JL, Sweeney M, Schwartz GG. Ray KK, et al. Am Heart J. 2019 Nov;217:72-83. doi: 10.1016/j.ahj.2019.08.001. Epub 2019 Aug 9. Am Heart J. 2019. PMID: 31520897 Free article. Clinical Trial.
Effect of Apabetalone Added to Standard Therapy on Major Adverse Cardiovascular Events in Patients With Recent Acute Coronary Syndrome and Type 2 Diabetes: A Randomized Clinical Trial.
Ray KK, Nicholls SJ, Buhr KA, Ginsberg HN, Johansson JO, Kalantar-Zadeh K, Kulikowski E, Toth PP, Wong N, Sweeney M, Schwartz GG; BETonMACE Investigators and Committees. Ray KK, et al. JAMA. 2020 Apr 28;323(16):1565-1573. doi: 10.1001/jama.2020.3308. JAMA. 2020. PMID: 32219359 Free PMC article. Clinical Trial.
RVX-208, an inducer of ApoA-I in humans, is a BET bromodomain antagonist.
McLure KG, Gesner EM, Tsujikawa L, Kharenko OA, Attwell S, Campeau E, Wasiak S, Stein A, White A, Fontano E, Suto RK, Wong NC, Wagner GS, Hansen HC, Young PR. McLure KG, et al. Among authors: wong nc. PLoS One. 2013 Dec 31;8(12):e83190. doi: 10.1371/journal.pone.0083190. eCollection 2013. PLoS One. 2013. PMID: 24391744 Free PMC article.
An evaluation of RVX-208 for the treatment of atherosclerosis.
Nikolic D, Rizzo M, Mikhailidis DP, Wong NC, Banach M. Nikolic D, et al. Among authors: wong nc. Expert Opin Investig Drugs. 2015;24(10):1389-98. doi: 10.1517/13543784.2015.1083010. Expert Opin Investig Drugs. 2015. PMID: 26364508 Review.
Stilbene analogs as inducers of apolipoprotein-I transcription.
Hansen HC, Chiacchia FS, Patel R, Wong NC, Khlebnikov V, Jankowska R, Patel K, Reddy MM. Hansen HC, et al. Among authors: wong nc. Eur J Med Chem. 2010 May;45(5):2018-23. doi: 10.1016/j.ejmech.2009.12.076. Epub 2010 Jan 14. Eur J Med Chem. 2010. PMID: 20106565
297 results