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Inhibiting phosphoglycerate dehydrogenase counteracts chemotherapeutic efficacy against MYCN-amplified neuroblastoma.
Arlt B, Zasada C, Baum K, Wuenschel J, Mastrobuoni G, Lodrini M, Astrahantseff K, Winkler A, Schulte JH, Finkler S, Forbes M, Hundsdoerfer P, Guergen D, Hoffmann J, Wolf J, Eggert A, Kempa S, Deubzer HE. Arlt B, et al. Among authors: wuenschel j. Int J Cancer. 2021 Mar 1;148(5):1219-1232. doi: 10.1002/ijc.33423. Epub 2020 Dec 17. Int J Cancer. 2021. PMID: 33284994 Free article.
Neuroblastoma cells depend on HDAC11 for mitotic cell cycle progression and survival.
Thole TM, Lodrini M, Fabian J, Wuenschel J, Pfeil S, Hielscher T, Kopp-Schneider A, Heinicke U, Fulda S, Witt O, Eggert A, Fischer M, Deubzer HE. Thole TM, et al. Among authors: wuenschel j. Cell Death Dis. 2017 Mar 2;8(3):e2635. doi: 10.1038/cddis.2017.49. Cell Death Dis. 2017. PMID: 28252645 Free PMC article.