Xia CQ - Search Results

1

Quantification of Four Efflux Drug Transporters in Liver and Kidney Across Species Using Targeted Quantitative Proteomics by Isotope Dilution NanoLC-MS/MS.

Fallon JK, Smith PC, Xia CQ, Kim MS. Fallon JK, et al. Among authors: xia cq. Pharm Res. 2016 Sep;33(9):2280-8. doi: 10.1007/s11095-016-1966-5. Epub 2016 Jun 29. Pharm Res. 2016. PMID: 27356525

2

Efflux transporter breast cancer resistance protein dominantly expresses on the membrane of red blood cells, hinders partitioning of its substrates into the cells, and alters drug-drug interaction profiles.

Shi P, Liao M, Chuang BC, Griffin R, Shi J, Hyer M, Fallon JK, Smith PC, Li C, Xia CQ. Shi P, et al. Among authors: xia cq. Xenobiotica. 2018 Nov;48(11):1173-1183. doi: 10.1080/00498254.2017.1397812. Epub 2017 Nov 16. Xenobiotica. 2018. PMID: 29098941

3

Sinusoidal Organic Anion-Transporting Polypeptide 1B1/1B3 and Bile Canalicular Multidrug Resistance-Associated Protein 2 Play an Essential Role in the Hepatobiliary Disposition of a Synthetic Cyclic Dinucleotide (STING Agonist).

Sandoval P, Chuang BC, Fallon JK, Smith PC, Chowdhury SK, Griffin RJ, Xia CQ, Iwasaki S, Chothe PP. Sandoval P, et al. Among authors: xia cq. AAPS J. 2022 Sep 19;24(6):99. doi: 10.1208/s12248-022-00745-7. AAPS J. 2022. PMID: 36123502

4

Prediction of Hepatic Efflux Transporter-Mediated Drug Interactions: When Is it Optimal to Measure Intracellular Unbound Fraction of Inhibitors?

Guo C, Yang K, Liao M, Xia CQ, Brouwer KR, Brouwer KLR. Guo C, et al. Among authors: xia cq. J Pharm Sci. 2017 Sep;106(9):2401-2406. doi: 10.1016/j.xphs.2017.04.054. Epub 2017 Apr 30. J Pharm Sci. 2017. PMID: 28465154 Free PMC article.

5

In Vitro Drug-Induced Liver Injury Prediction: Criteria Optimization of Efflux Transporter IC50 and Physicochemical Properties.

Yucha RW, He K, Shi Q, Cai L, Nakashita Y, Xia CQ, Liao M. Yucha RW, et al. Among authors: xia cq. Toxicol Sci. 2017 Jun 1;157(2):487-499. doi: 10.1093/toxsci/kfx060. Toxicol Sci. 2017. PMID: 28369588

6

Preclinical absorption, distribution, metabolism, excretion and pharmacokinetics of a novel selective inhibitor of breast cancer resistance protein (BCRP).

Liao M, Chuang BC, Zhu Q, Li Y, Guan E, Yu S, Yang J, Prakash S, Xia CQ. Liao M, et al. Among authors: xia cq. Xenobiotica. 2018 May;48(5):467-477. doi: 10.1080/00498254.2017.1328147. Epub 2017 May 31. Xenobiotica. 2018. PMID: 28485193

7

P-glycoprotein and breast cancer resistance protein affect disposition of tandutinib, a tyrosine kinase inhibitor.

Yang JJ, Milton MN, Yu S, Liao M, Liu N, Wu JT, Gan L, Balani SK, Lee FW, Prakash S, Xia CQ. Yang JJ, et al. Among authors: xia cq. Drug Metab Lett. 2010 Dec;4(4):201-12. doi: 10.2174/187231210792928279. Drug Metab Lett. 2010. PMID: 20670210

8

Drug efflux transporters and multidrug resistance in acute leukemia: therapeutic impact and novel approaches to mediation.

Xia CQ, Smith PG. Xia CQ, et al. Mol Pharmacol. 2012 Dec;82(6):1008-21. doi: 10.1124/mol.112.079129. Epub 2012 Jul 23. Mol Pharmacol. 2012. PMID: 22826468 Review.

9

Comparison of species differences of P-glycoproteins in beagle dog, rhesus monkey, and human using Atpase activity assays.

Xia CQ, Xiao G, Liu N, Pimprale S, Fox L, Patten CJ, Crespi CL, Miwa G, Gan LS. Xia CQ, et al. Mol Pharm. 2006 Jan-Feb;3(1):78-86. doi: 10.1021/mp050034j. Mol Pharm. 2006. PMID: 16686372

10

Comparison of uptake transporter functions in hepatocytes in different species to determine the optimal model for evaluating drug transporter activities in humans.

Liao M, Zhu Q, Zhu A, Gemski C, Ma B, Guan E, Li AP, Xiao G, Xia CQ. Liao M, et al. Among authors: xia cq. Xenobiotica. 2019 Jul;49(7):852-862. doi: 10.1080/00498254.2018.1512017. Epub 2018 Sep 21. Xenobiotica. 2019. PMID: 30132394

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