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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
1998 1
2002 1
2004 1
2005 1
2006 1
2007 2
2008 1
2009 2
2010 3
2011 2
2012 2
2013 4
2014 2
2015 2
2016 2
2017 2
2018 6
2019 4
2020 5
2022 2
2023 2
2024 0

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47 results

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Page 1
Glucagon stimulates gluconeogenesis by INSP3R1-mediated hepatic lipolysis.
Perry RJ, Zhang D, Guerra MT, Brill AL, Goedeke L, Nasiri AR, Rabin-Court A, Wang Y, Peng L, Dufour S, Zhang Y, Zhang XM, Butrico GM, Toussaint K, Nozaki Y, Cline GW, Petersen KF, Nathanson MH, Ehrlich BE, Shulman GI. Perry RJ, et al. Among authors: zhang xm. Nature. 2020 Mar;579(7798):279-283. doi: 10.1038/s41586-020-2074-6. Epub 2020 Mar 4. Nature. 2020. PMID: 32132708 Free PMC article.
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase.
Madiraju AK, Erion DM, Rahimi Y, Zhang XM, Braddock DT, Albright RA, Prigaro BJ, Wood JL, Bhanot S, MacDonald MJ, Jurczak MJ, Camporez JP, Lee HY, Cline GW, Samuel VT, Kibbey RG, Shulman GI. Madiraju AK, et al. Among authors: zhang xm. Nature. 2014 Jun 26;510(7506):542-6. doi: 10.1038/nature13270. Epub 2014 May 21. Nature. 2014. PMID: 24847880 Free PMC article.
Inhibition of HSD17B13 protects against liver fibrosis by inhibition of pyrimidine catabolism in nonalcoholic steatohepatitis.
Luukkonen PK, Sakuma I, Gaspar RC, Mooring M, Nasiri A, Kahn M, Zhang XM, Zhang D, Sammalkorpi H, Penttilä AK, Orho-Melander M, Arola J, Juuti A, Zhang X, Yimlamai D, Yki-Järvinen H, Petersen KF, Shulman GI. Luukkonen PK, et al. Among authors: zhang xm. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2217543120. doi: 10.1073/pnas.2217543120. Epub 2023 Jan 20. Proc Natl Acad Sci U S A. 2023. PMID: 36669104 Free PMC article.
Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo.
Madiraju AK, Qiu Y, Perry RJ, Rahimi Y, Zhang XM, Zhang D, Camporez JG, Cline GW, Butrico GM, Kemp BE, Casals G, Steinberg GR, Vatner DF, Petersen KF, Shulman GI. Madiraju AK, et al. Among authors: zhang xm. Nat Med. 2018 Sep;24(9):1384-1394. doi: 10.1038/s41591-018-0125-4. Epub 2018 Jul 23. Nat Med. 2018. PMID: 30038219 Free PMC article.
The PNPLA3 I148M variant increases ketogenesis and decreases hepatic de novo lipogenesis and mitochondrial function in humans.
Luukkonen PK, Porthan K, Ahlholm N, Rosqvist F, Dufour S, Zhang XM, Lehtimäki TE, Seppänen W, Orho-Melander M, Hodson L, Petersen KF, Shulman GI, Yki-Järvinen H. Luukkonen PK, et al. Among authors: zhang xm. Cell Metab. 2023 Nov 7;35(11):1887-1896.e5. doi: 10.1016/j.cmet.2023.10.008. Epub 2023 Oct 30. Cell Metab. 2023. PMID: 37909034 Free article.
Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease.
Luukkonen PK, Dufour S, Lyu K, Zhang XM, Hakkarainen A, Lehtimäki TE, Cline GW, Petersen KF, Shulman GI, Yki-Järvinen H. Luukkonen PK, et al. Among authors: zhang xm. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7347-7354. doi: 10.1073/pnas.1922344117. Epub 2020 Mar 16. Proc Natl Acad Sci U S A. 2020. PMID: 32179679 Free PMC article.
Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis.
LaMoia TE, Butrico GM, Kalpage HA, Goedeke L, Hubbard BT, Vatner DF, Gaspar RC, Zhang XM, Cline GW, Nakahara K, Woo S, Shimada A, Hüttemann M, Shulman GI. LaMoia TE, et al. Among authors: zhang xm. Proc Natl Acad Sci U S A. 2022 Mar 8;119(10):e2122287119. doi: 10.1073/pnas.2122287119. Epub 2022 Mar 1. Proc Natl Acad Sci U S A. 2022. PMID: 35238637 Free PMC article.
Metabolic control analysis of hepatic glycogen synthesis in vivo.
Nozaki Y, Petersen MC, Zhang D, Vatner DF, Perry RJ, Abulizi A, Haedersdal S, Zhang XM, Butrico GM, Samuel VT, Mason GF, Cline GW, Petersen KF, Rothman DL, Shulman GI. Nozaki Y, et al. Among authors: zhang xm. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):8166-8176. doi: 10.1073/pnas.1921694117. Epub 2020 Mar 18. Proc Natl Acad Sci U S A. 2020. PMID: 32188779 Free PMC article.
47 results