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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2008 2
2009 2
2010 2
2011 3
2012 1
2013 1
2014 3
2015 5
2016 3
2017 6
2018 4
2019 9
2020 10
2021 15
2022 20
2023 22
2024 5

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107 results

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Page 1
Discovery of a first-in-class EZH2 selective degrader.
Ma A, Stratikopoulos E, Park KS, Wei J, Martin TC, Yang X, Schwarz M, Leshchenko V, Rialdi A, Dale B, Lagana A, Guccione E, Parekh S, Parsons R, Jin J. Ma A, et al. Among authors: yang x. Nat Chem Biol. 2020 Feb;16(2):214-222. doi: 10.1038/s41589-019-0421-4. Epub 2019 Dec 9. Nat Chem Biol. 2020. PMID: 31819273 Free PMC article.
Distinct CDK6 complexes determine tumor cell response to CDK4/6 inhibitors and degraders.
Wu X, Yang X, Xiong Y, Li R, Ito T, Ahmed TA, Karoulia Z, Adamopoulos C, Wang H, Wang L, Xie L, Liu J, Ueberheide B, Aaronson SA, Chen X, Buchanan SG, Sellers WR, Jin J, Poulikakos PI. Wu X, et al. Among authors: yang x. Nat Cancer. 2021 Apr;2(4):429-443. doi: 10.1038/s43018-021-00174-z. Epub 2021 Mar 1. Nat Cancer. 2021. PMID: 34568836 Free PMC article.
Inflammasome activity is controlled by ZBTB16-dependent SUMOylation of ASC.
Dong D, Du Y, Fei X, Yang H, Li X, Yang X, Ma J, Huang S, Ma Z, Zheng J, Chan DW, Shi L, Li Y, Irving AT, Yuan X, Liu X, Ni P, Hu Y, Meng G, Peng Y, Sadler A, Xu D. Dong D, et al. Among authors: yang x. Nat Commun. 2023 Dec 20;14(1):8465. doi: 10.1038/s41467-023-43945-1. Nat Commun. 2023. PMID: 38123560 Free PMC article.
Stimuli-activatable PROTACs for precise protein degradation and cancer therapy.
Gao J, Yang L, Lei S, Zhou F, Nie H, Peng B, Xu T, Chen X, Yang X, Sheng C, Rao Y, Pu K, Jin J, Xu Z, Yu H. Gao J, et al. Among authors: yang x. Sci Bull (Beijing). 2023 May 30;68(10):1069-1085. doi: 10.1016/j.scib.2023.04.028. Epub 2023 Apr 26. Sci Bull (Beijing). 2023. PMID: 37169612 Review.
An MDM2 degrader for treatment of acute leukemias.
Marcellino BK, Yang X, Ümit Kaniskan H, Brady C, Chen H, Chen K, Qiu X, Clementelli C, Herschbein L, Li Z, Elghaity-Beckley S, Arandela J, Kelly B, Hoffman R, Liu J, Xiong Y, Jin J, Shih AH. Marcellino BK, et al. Among authors: yang x. Leukemia. 2023 Feb;37(2):370-378. doi: 10.1038/s41375-022-01735-6. Epub 2022 Oct 29. Leukemia. 2023. PMID: 36309559 Free PMC article.
Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase.
Wang Q, Wu J, Wang H, Gao Y, Liu Q, Mu A, Ji W, Yan L, Zhu Y, Zhu C, Fang X, Yang X, Huang Y, Gao H, Liu F, Ge J, Sun Q, Yang X, Xu W, Liu Z, Yang H, Lou Z, Jiang B, Guddat LW, Gong P, Rao Z. Wang Q, et al. Among authors: yang x. Cell. 2020 Jul 23;182(2):417-428.e13. doi: 10.1016/j.cell.2020.05.034. Epub 2020 May 22. Cell. 2020. PMID: 32526208 Free PMC article.
107 results