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SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors.
Wang X, Chen Z, Xu J, Tang S, An N, Jiang L, Zhang Y, Zhang S, Zhang Q, Shen Y, Chen S, Lan X, Wang T, Zhai L, Cao S, Guo S, Liu Y, Bi A, Chen Y, Gai X, Duan Y, Zheng Y, Fu Y, Li Y, Yuan L, Tong L, Mo K, Wang M, Lin SH, Tan M, Luo C, Chen Y, Liu J, Zhang Q, Li L, Huang M. Wang X, et al. Among authors: lan x. Cell Res. 2022 Jul;32(7):638-658. doi: 10.1038/s41422-022-00650-w. Epub 2022 Apr 22. Cell Res. 2022. PMID: 35459936 Free PMC article.
Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis.
Tang S, Duan Y, Yuan T, Hu Y, Yuan L, Shen N, Fu Y, Pu C, Wang X, Xu J, Lan X, Zheng Y, Zhou Y, Zhu H, Ding J, Geng M, Huang M. Tang S, et al. Among authors: lan x. Pharmacol Res. 2023 Nov;197:106955. doi: 10.1016/j.phrs.2023.106955. Epub 2023 Oct 14. Pharmacol Res. 2023. PMID: 37820855 Free article.
Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer.
Jin N, Bi A, Lan X, Xu J, Wang X, Liu Y, Wang T, Tang S, Zeng H, Chen Z, Tan M, Ai J, Xie H, Zhang T, Liu D, Huang R, Song Y, Leung EL, Yao X, Ding J, Geng M, Lin SH, Huang M. Jin N, et al. Among authors: lan x. Nat Commun. 2019 Jun 20;10(1):2701. doi: 10.1038/s41467-019-10427-2. Nat Commun. 2019. PMID: 31221965 Free PMC article.
11 results