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Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation.
Cell Metab. 2024 Jan 2;36(1):176-192.e10. doi: 10.1016/j.cmet.2023.12.010.
Cell Metab. 2024.
PMID: 38171332
Mitochondrial C1qbp promotes differentiation of effector CD8+ T cells via metabolic-epigenetic reprogramming.
Zhai X, Liu K, Fang H, Zhang Q, Gao X, Liu F, Zhou S, Wang X, Niu Y, Hong Y, Lin SH, Liu WH, Xiao C, Li Q, Xiao N.
Zhai X, et al.
Sci Adv. 2021 Dec 3;7(49):eabk0490. doi: 10.1126/sciadv.abk0490. Epub 2021 Dec 3.
Sci Adv. 2021.
PMID: 34860557
Free PMC article.
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