Xu M - Search Results

1

Structural insights into inhibitory mechanism of human excitatory amino acid transporter EAAT2.

Kato T, Kusakizako T, Jin C, Zhou X, Ohgaki R, Quan L, Xu M, Okuda S, Kobayashi K, Yamashita K, Nishizawa T, Kanai Y, Nureki O. Kato T, et al. Among authors: xu m. Nat Commun. 2022 Aug 11;13(1):4714. doi: 10.1038/s41467-022-32442-6. Nat Commun. 2022. PMID: 35953475 Free PMC article.

2

Up-Regulation of LAT1 during Antiandrogen Therapy Contributes to Progression in Prostate Cancer Cells.

Xu M, Sakamoto S, Matsushima J, Kimura T, Ueda T, Mizokami A, Kanai Y, Ichikawa T. Xu M, et al. J Urol. 2016 May;195(5):1588-1597. doi: 10.1016/j.juro.2015.11.071. Epub 2015 Dec 9. J Urol. 2016. PMID: 26682754

3

Expression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma.

Maimaiti M, Sakamoto S, Yamada Y, Sugiura M, Rii J, Takeuchi N, Imamura Y, Furihata T, Ando K, Higuchi K, Xu M, Sazuka T, Nakamura K, Kaneda A, Kanai Y, Kyprianou N, Ikehara Y, Anzai N, Ichikawa T. Maimaiti M, et al. Among authors: xu m. Sci Rep. 2020 Jan 28;10(1):1292. doi: 10.1038/s41598-020-58136-x. Sci Rep. 2020. PMID: 31992742 Free PMC article.

4

Interaction of Halogenated Tyrosine/Phenylalanine Derivatives with Organic Anion Transporter 1 in the Renal Handling of Tumor Imaging Probes.

Jin C, Wei L, Ohgaki R, Tominaga H, Xu M, Okuda S, Okanishi H, Kawamoto Y, He X, Nagamori S, Kanai Y. Jin C, et al. Among authors: xu m. J Pharmacol Exp Ther. 2020 Dec;375(3):451-462. doi: 10.1124/jpet.120.000235. Epub 2020 Sep 27. J Pharmacol Exp Ther. 2020. PMID: 32981893

5

Functional analysis of LAT3 in prostate cancer: Its downstream target and relationship with androgen receptor.

Rii J, Sakamoto S, Sugiura M, Kanesaka M, Fujimoto A, Yamada Y, Maimaiti M, Ando K, Wakai K, Xu M, Imamura Y, Shindo N, Hirota T, Kaneda A, Kanai Y, Ikehara Y, Anzai N, Ichikawa T. Rii J, et al. Among authors: xu m. Cancer Sci. 2021 Sep;112(9):3871-3883. doi: 10.1111/cas.14991. Epub 2021 Jul 8. Cancer Sci. 2021. PMID: 34050700 Free PMC article.

6

Functional coupling of organic anion transporter OAT10 (SLC22A13) and monocarboxylate transporter MCT1 (SLC16A1) influencing the transport function of OAT10.

Ohtsu N, Ohgaki R, Jin C, Xu M, Okanishi H, Takahashi R, Matsui A, Kishimoto W, Ishiguro N, Kanai Y. Ohtsu N, et al. Among authors: xu m. J Pharmacol Sci. 2022 Sep;150(1):41-48. doi: 10.1016/j.jphs.2022.06.003. Epub 2022 Jun 17. J Pharmacol Sci. 2022. PMID: 35926947 Free article.

7

Pharmacologic inhibition of LAT1 predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells.

Nishikubo K, Ohgaki R, Okanishi H, Okuda S, Xu M, Endou H, Kanai Y. Nishikubo K, et al. Among authors: xu m. J Cell Mol Med. 2022 Oct;26(20):5246-5256. doi: 10.1111/jcmm.17553. Epub 2022 Sep 7. J Cell Mol Med. 2022. PMID: 36071551 Free PMC article.

8

Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of L-type amino acid transporter 1.

Okanishi H, Ohgaki R, Xu M, Endou H, Kanai Y. Okanishi H, et al. Among authors: xu m. Cancer Metab. 2022 Nov 10;10(1):18. doi: 10.1186/s40170-022-00295-8. Cancer Metab. 2022. PMID: 36357940 Free PMC article.

9

Combination effects of amino acid transporter LAT1 inhibitor nanvuranlat and cytotoxic anticancer drug gemcitabine on pancreatic and biliary tract cancer cells.

Nishikubo K, Ohgaki R, Liu X, Okanishi H, Xu M, Endou H, Kanai Y. Nishikubo K, et al. Among authors: xu m. Cancer Cell Int. 2023 Jun 15;23(1):116. doi: 10.1186/s12935-023-02957-z. Cancer Cell Int. 2023. PMID: 37322479 Free PMC article.

10

Inhibition of cancer-type amino acid transporter LAT1 suppresses B16-F10 melanoma metastasis in mouse models.

Shi Z, Kaneda-Nakashima K, Ohgaki R, Xu M, Okanishi H, Endou H, Nagamori S, Kanai Y. Shi Z, et al. Among authors: xu m. Sci Rep. 2023 Aug 25;13(1):13943. doi: 10.1038/s41598-023-41096-3. Sci Rep. 2023. PMID: 37626086 Free PMC article.

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