Xu TH - Search Results

1

A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.

Ma H, Duan J, Ke J, He Y, Gu X, Xu TH, Yu H, Wang Y, Brunzelle JS, Jiang Y, Rothbart SB, Xu HE, Li J, Melcher K. Ma H, et al. Among authors: xu he, xu th. Sci Adv. 2017 Jun 2;3(6):e1601217. doi: 10.1126/sciadv.1601217. eCollection 2017 Jun. Sci Adv. 2017. PMID: 28630893 Free PMC article.

2

Crystal structures of two phytohormone signal-transducing α/β hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.

Zhao LH, Zhou XE, Wu ZS, Yi W, Xu Y, Li S, Xu TH, Liu Y, Chen RZ, Kovach A, Kang Y, Hou L, He Y, Xie C, Song W, Zhong D, Xu Y, Wang Y, Li J, Zhang C, Melcher K, Xu HE. Zhao LH, et al. Among authors: xu he, xu th, xu y. Cell Res. 2013 Mar;23(3):436-9. doi: 10.1038/cr.2013.19. Epub 2013 Feb 5. Cell Res. 2013. PMID: 23381136 Free PMC article. No abstract available.

3

Alzheimer's disease-associated mutations increase amyloid precursor protein resistance to γ-secretase cleavage and the Aβ42/Aβ40 ratio.

Xu TH, Yan Y, Kang Y, Jiang Y, Melcher K, Xu HE. Xu TH, et al. Among authors: xu he. Cell Discov. 2016 Aug 23;2:16026. doi: 10.1038/celldisc.2016.26. eCollection 2016. Cell Discov. 2016. PMID: 27625790 Free PMC article.

4

Defining the minimum substrate and charge recognition model of gamma-secretase.

Yan Y, Xu TH, Melcher K, Xu HE. Yan Y, et al. Among authors: xu he, xu th. Acta Pharmacol Sin. 2017 Oct;38(10):1412-1424. doi: 10.1038/aps.2017.35. Epub 2017 Apr 17. Acta Pharmacol Sin. 2017. PMID: 28414207 Free PMC article.

5

Amyloid beta: structure, biology and structure-based therapeutic development.

Chen GF, Xu TH, Yan Y, Zhou YR, Jiang Y, Melcher K, Xu HE. Chen GF, et al. Among authors: xu he, xu th. Acta Pharmacol Sin. 2017 Sep;38(9):1205-1235. doi: 10.1038/aps.2017.28. Epub 2017 Jul 17. Acta Pharmacol Sin. 2017. PMID: 28713158 Free PMC article. Review.

6

Dimerization of the transmembrane domain of amyloid precursor protein is determined by residues around the γ-secretase cleavage sites.

Yan Y, Xu TH, Harikumar KG, Miller LJ, Melcher K, Xu HE. Yan Y, et al. Among authors: xu he, xu th. J Biol Chem. 2017 Sep 22;292(38):15826-15837. doi: 10.1074/jbc.M117.789669. Epub 2017 Aug 8. J Biol Chem. 2017. PMID: 28790170 Free PMC article.

7

γ-Secretase Epsilon-cleavage Assay.

Xu TH, Yan Y, Harikumar KG, Miller LJ, Melcher K, Xu HE. Xu TH, et al. Among authors: xu he. Bio Protoc. 2017 Nov 20;7(22):e2900. doi: 10.21769/BioProtoc.2900. Bio Protoc. 2017. PMID: 29392164 Free PMC article.

8

Detection of Membrane Protein Interactions by Cell-based Tango Assays.

Yan Y, Xu TH, Harikumar KG, Miller LJ, Melcher K, Xu HE. Yan Y, et al. Among authors: xu he, xu th. Bio Protoc. 2017 Nov 20;7(22):e2903. doi: 10.21769/BioProtoc.2903. Bio Protoc. 2017. PMID: 29392165 Free PMC article.

9

Streptavidin Bead Pulldown Assay to Determine Protein Homooligomerization.

Xu TH, Yan Y, Harikumar KG, Miller LJ, Melcher K, Xu HE. Xu TH, et al. Among authors: xu he. Bio Protoc. 2017 Nov 20;7(22):e2901. doi: 10.21769/BioProtoc.2901. Bio Protoc. 2017. PMID: 29392166 Free PMC article.

10

Bioluminescence Resonance Energy Transfer (BRET) Assay for Determination of Molecular Interactions in Living Cells.

Harikumar KG, Yan Y, Xu TH, Melcher K, Xu HE, Miller LJ. Harikumar KG, et al. Among authors: xu he, xu th. Bio Protoc. 2017 Nov 20;7(22):e2904. doi: 10.21769/BioProtoc.2904. Bio Protoc. 2017. PMID: 29423426 Free PMC article.

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