Yaffe MB - Search Results

1

Peptoid-Peptide hybrid ligands targeting the polo box domain of polo-like kinase 1.

Liu F, Park JE, Qian WJ, Lim D, Scharow A, Berg T, Yaffe MB, Lee KS, Burke TR Jr. Liu F, et al. Among authors: yaffe mb. Chembiochem. 2012 Jun 18;13(9):1291-6. doi: 10.1002/cbic.201200206. Epub 2012 May 8. Chembiochem. 2012. PMID: 22570300 Free PMC article.

2

The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain.

Elia AE, Rellos P, Haire LF, Chao JW, Ivins FJ, Hoepker K, Mohammad D, Cantley LC, Smerdon SJ, Yaffe MB. Elia AE, et al. Among authors: yaffe mb. Cell. 2003 Oct 3;115(1):83-95. doi: 10.1016/s0092-8674(03)00725-6. Cell. 2003. PMID: 14532005 Free article.

3

Proteomic screen defines the Polo-box domain interactome and identifies Rock2 as a Plk1 substrate.

Lowery DM, Clauser KR, Hjerrild M, Lim D, Alexander J, Kishi K, Ong SE, Gammeltoft S, Carr SA, Yaffe MB. Lowery DM, et al. Among authors: yaffe mb. EMBO J. 2007 May 2;26(9):2262-73. doi: 10.1038/sj.emboj.7601683. Epub 2007 Apr 19. EMBO J. 2007. PMID: 17446864 Free PMC article.

4

Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery.

Macůrek L, Lindqvist A, Lim D, Lampson MA, Klompmaker R, Freire R, Clouin C, Taylor SS, Yaffe MB, Medema RH. Macůrek L, et al. Among authors: yaffe mb. Nature. 2008 Sep 4;455(7209):119-23. doi: 10.1038/nature07185. Epub 2008 Jul 9. Nature. 2008. PMID: 18615013

5

Polo-like kinase-1 controls Aurora A destruction by activating APC/C-Cdh1.

van Leuken R, Clijsters L, van Zon W, Lim D, Yao X, Wolthuis RM, Yaffe MB, Medema RH, van Vugt MA. van Leuken R, et al. Among authors: yaffe mb. PLoS One. 2009;4(4):e5282. doi: 10.1371/journal.pone.0005282. Epub 2009 Apr 23. PLoS One. 2009. PMID: 19390576 Free PMC article.

6

Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.

Yun SM, Moulaei T, Lim D, Bang JK, Park JE, Shenoy SR, Liu F, Kang YH, Liao C, Soung NK, Lee S, Yoon DY, Lim Y, Lee DH, Otaka A, Appella E, McMahon JB, Nicklaus MC, Burke TR Jr, Yaffe MB, Wlodawer A, Lee KS. Yun SM, et al. Among authors: yaffe mb. Nat Struct Mol Biol. 2009 Aug;16(8):876-82. doi: 10.1038/nsmb.1628. Epub 2009 Jul 13. Nat Struct Mol Biol. 2009. PMID: 19597481 Free PMC article.

7

Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel.

Liu F, Park JE, Qian WJ, Lim D, Gräber M, Berg T, Yaffe MB, Lee KS, Burke TR Jr. Liu F, et al. Among authors: yaffe mb. Nat Chem Biol. 2011 Jul 17;7(9):595-601. doi: 10.1038/nchembio.614. Nat Chem Biol. 2011. PMID: 21765407 Free PMC article.

8

Identification of high affinity polo-like kinase 1 (Plk1) polo-box domain binding peptides using oxime-based diversification.

Liu F, Park JE, Qian WJ, Lim D, Scharow A, Berg T, Yaffe MB, Lee KS, Burke TR Jr. Liu F, et al. Among authors: yaffe mb. ACS Chem Biol. 2012 May 18;7(5):805-10. doi: 10.1021/cb200469a. Epub 2012 Feb 14. ACS Chem Biol. 2012. PMID: 22292814 Free PMC article.

9

Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1.

Murugan RN, Park JE, Lim D, Ahn M, Cheong C, Kwon T, Nam KY, Choi SH, Kim BY, Yoon DY, Yaffe MB, Yu DY, Lee KS, Bang JK. Murugan RN, et al. Among authors: yaffe mb. Bioorg Med Chem. 2013 May 1;21(9):2623-34. doi: 10.1016/j.bmc.2013.02.020. Epub 2013 Feb 27. Bioorg Med Chem. 2013. PMID: 23498919 Free PMC article.

10

Peptide-based inhibitors of Plk1 polo-box domain containing mono-anionic phosphothreonine esters and their pivaloyloxymethyl prodrugs.

Qian WJ, Park JE, Lim D, Park SY, Lee KW, Yaffe MB, Lee KS, Burke TR Jr. Qian WJ, et al. Among authors: yaffe mb. Chem Biol. 2013 Oct 24;20(10):1255-64. doi: 10.1016/j.chembiol.2013.09.005. Epub 2013 Oct 10. Chem Biol. 2013. PMID: 24120332 Free PMC article. Retracted.

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