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Sirt1 counteracts decrease in membrane phospholipid unsaturation and diastolic dysfunction during saturated fatty acid overload.
Yamamoto T, Endo J, Kataoka M, Matsuhashi T, Katsumata Y, Shirakawa K, Yoshida N, Isobe S, Moriyama H, Goto S, Yamashita K, Ohto-Nakanishi T, Nakanishi H, Shimanaka Y, Kono N, Shinmura K, Arai H, Fukuda K, Sano M. Yamamoto T, et al. J Mol Cell Cardiol. 2019 Aug;133:1-11. doi: 10.1016/j.yjmcc.2019.05.019. Epub 2019 May 27. J Mol Cell Cardiol. 2019. PMID: 31145942
Adventitial CXCL1/G-CSF expression in response to acute aortic dissection triggers local neutrophil recruitment and activation leading to aortic rupture.
Anzai A, Shimoda M, Endo J, Kohno T, Katsumata Y, Matsuhashi T, Yamamoto T, Ito K, Yan X, Shirakawa K, Shimizu-Hirota R, Yamada Y, Ueha S, Shinmura K, Okada Y, Fukuda K, Sano M. Anzai A, et al. Among authors: yamamoto t. Circ Res. 2015 Feb 13;116(4):612-23. doi: 10.1161/CIRCRESAHA.116.304918. Epub 2015 Jan 6. Circ Res. 2015. PMID: 25563839
Indispensable role of endothelial nitric oxide synthase in caloric restriction-induced cardioprotection against ischemia-reperfusion injury.
Shinmura K, Tamaki K, Ito K, Yan X, Yamamoto T, Katsumata Y, Matsuhashi T, Sano M, Fukuda K, Suematsu M, Ishii I. Shinmura K, et al. Among authors: yamamoto t. Am J Physiol Heart Circ Physiol. 2015 Apr 15;308(8):H894-903. doi: 10.1152/ajpheart.00333.2014. Epub 2015 Feb 13. Am J Physiol Heart Circ Physiol. 2015. PMID: 25681423 Free article.
Activation of pyruvate dehydrogenase by dichloroacetate has the potential to induce epigenetic remodeling in the heart.
Matsuhashi T, Hishiki T, Zhou H, Ono T, Kaneda R, Iso T, Yamaguchi A, Endo J, Katsumata Y, Atsushi A, Yamamoto T, Shirakawa K, Yan X, Shinmura K, Suematsu M, Fukuda K, Sano M. Matsuhashi T, et al. Among authors: yamamoto t. J Mol Cell Cardiol. 2015 May;82:116-24. doi: 10.1016/j.yjmcc.2015.02.021. Epub 2015 Mar 2. J Mol Cell Cardiol. 2015. PMID: 25744081
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