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Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses.
Urano W, Taniguchi A, Yamanaka H, Tanaka E, Nakajima H, Matsuda Y, Akama H, Kitamura Y, Kamatani N. Urano W, et al. Among authors: yamanaka h. Pharmacogenetics. 2002 Apr;12(3):183-90. doi: 10.1097/00008571-200204000-00002. Pharmacogenetics. 2002. PMID: 11927833
Rheumatoid arthritis and angiogenesis.
Yamanaka H. Yamanaka H. Intern Med. 2003 Mar;42(3):297-9. doi: 10.2169/internalmedicine.42.297. Intern Med. 2003. PMID: 12705803 Free article. No abstract available.
Influence of methotrexate dose on its efficacy and safety in rheumatoid arthritis patients: evidence based on the variety of prescribing approaches among practicing Japanese rheumatologists in a single institute-based large observational cohort (IORRA).
Yamanaka H, Inoue E, Tanaka E, Nakajima A, Taniguchi A, Terai C, Hara M, Tomatsu T, Kamatani N. Yamanaka H, et al. Mod Rheumatol. 2007;17(2):98-105. doi: 10.1007/s10165-006-0546-7. Epub 2007 Apr 20. Mod Rheumatol. 2007. PMID: 17437163 Clinical Trial.
Validation of the associations between single nucleotide polymorphisms or haplotypes and responses to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: a proposal for prospective pharmacogenomic study in clinical practice.
Taniguchi A, Urano W, Tanaka E, Furihata S, Kamitsuji S, Inoue E, Yamanaka M, Yamanaka H, Kamatani N. Taniguchi A, et al. Among authors: yamanaka h, yamanaka m. Pharmacogenet Genomics. 2007 Jun;17(6):383-90. doi: 10.1097/01.fpc.0000236326.80809.b1. Pharmacogenet Genomics. 2007. PMID: 17502830
1,881 results