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Constitutive adipocyte mTORC1 activation enhances mitochondrial activity and reduces visceral adiposity in mice.
Magdalon J, Chimin P, Belchior T, Neves RX, Vieira-Lara MA, Andrade ML, Farias TS, Bolsoni-Lopes A, Paschoal VA, Yamashita AS, Kowaltowski AJ, Festuccia WT. Magdalon J, et al. Among authors: yamashita as. Biochim Biophys Acta. 2016 May;1861(5):430-8. doi: 10.1016/j.bbalip.2016.02.023. Epub 2016 Feb 27. Biochim Biophys Acta. 2016. PMID: 26923434
mTORC1 inhibition with rapamycin exacerbates adipose tissue inflammation in obese mice and dissociates macrophage phenotype from function.
Paschoal VA, Amano MT, Belchior T, Magdalon J, Chimin P, Andrade ML, Ortiz-Silva M, Castro É, Yamashita AS, Rosa Neto JC, Câmara NO, Festuccia WT. Paschoal VA, et al. Among authors: yamashita as. Immunobiology. 2017 Feb;222(2):261-271. doi: 10.1016/j.imbio.2016.09.014. Epub 2016 Sep 28. Immunobiology. 2017. PMID: 27692982
Adipocyte mTORC1 deficiency promotes adipose tissue inflammation and NLRP3 inflammasome activation via oxidative stress and de novo ceramide synthesis.
Chimin P, Andrade ML, Belchior T, Paschoal VA, Magdalon J, Yamashita AS, Castro É, Castoldi A, Chaves-Filho AB, Yoshinaga MY, Miyamoto S, Câmara NO, Festuccia WT. Chimin P, et al. Among authors: yamashita as. J Lipid Res. 2017 Sep;58(9):1797-1807. doi: 10.1194/jlr.M074518. Epub 2017 Jul 5. J Lipid Res. 2017. PMID: 28679588 Free PMC article.
White adipose tissue cells and the progression of cachexia: inflammatory pathways.
Neves RX, Rosa-Neto JC, Yamashita AS, Matos-Neto EM, Riccardi DM, Lira FS, Batista ML Jr, Seelaender M. Neves RX, et al. Among authors: yamashita as. J Cachexia Sarcopenia Muscle. 2016 May;7(2):193-203. doi: 10.1002/jcsm.12041. Epub 2015 Jul 7. J Cachexia Sarcopenia Muscle. 2016. PMID: 27493872 Free PMC article.
Doxorubicin caused severe hyperglycaemia and insulin resistance, mediated by inhibition in AMPk signalling in skeletal muscle.
de Lima Junior EA, Yamashita AS, Pimentel GD, De Sousa LG, Santos RV, Gonçalves CL, Streck EL, de Lira FS, Rosa Neto JC. de Lima Junior EA, et al. Among authors: yamashita as. J Cachexia Sarcopenia Muscle. 2016 Dec;7(5):615-625. doi: 10.1002/jcsm.12104. Epub 2016 Feb 15. J Cachexia Sarcopenia Muscle. 2016. PMID: 27239415 Free PMC article.
34 results