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Tumors defective in homologous recombination rely on oxidative metabolism: relevance to treatments with PARP inhibitors.
Lahiguera Á, Hyroššová P, Figueras A, Garzón D, Moreno R, Soto-Cerrato V, McNeish I, Serra V, Lazaro C, Barretina P, Brunet J, Menéndez J, Matias-Guiu X, Vidal A, Villanueva A, Taylor-Harding B, Tanaka H, Orsulic S, Junza A, Yanes O, Muñoz-Pinedo C, Palomero L, Pujana MÀ, Perales JC, Viñals F. Lahiguera Á, et al. Among authors: yanes o. EMBO Mol Med. 2020 Jun 8;12(6):e11217. doi: 10.15252/emmm.201911217. Epub 2020 May 13. EMBO Mol Med. 2020. PMID: 32400970 Free PMC article.
Epigenetic loss of the endoplasmic reticulum-associated degradation inhibitor SVIP induces cancer cell metabolic reprogramming.
Llinàs-Arias P, Rosselló-Tortella M, López-Serra P, Pérez-Salvia M, Setién F, Marin S, Muñoz JP, Junza A, Capellades J, Calleja-Cervantes ME, Ferreira HJ, de Moura MC, Srbic M, Martínez-Cardús A, de la Torre C, Villanueva A, Cascante M, Yanes O, Zorzano A, Moutinho C, Esteller M. Llinàs-Arias P, et al. Among authors: yanes o. JCI Insight. 2019 Mar 7;5(8):e125888. doi: 10.1172/jci.insight.125888. JCI Insight. 2019. PMID: 30843871 Free PMC article.
Hepatic Lipidomics and Molecular Imaging in a Murine Non-Alcoholic Fatty Liver Disease Model: Insights into Molecular Mechanisms.
Rodríguez-Calvo R, Samino S, Girona J, Martínez-Micaelo N, Ràfols P, García-Altares M, Guaita-Esteruelas S, Junza A, Heras M, Yanes O, Correig X, Masana L. Rodríguez-Calvo R, et al. Among authors: yanes o. Biomolecules. 2020 Sep 3;10(9):1275. doi: 10.3390/biom10091275. Biomolecules. 2020. PMID: 32899418 Free PMC article.
Endogenous Retroelement Activation by Epigenetic Therapy Reverses the Warburg Effect and Elicits Mitochondrial-Mediated Cancer Cell Death.
Fresquet V, Garcia-Barchino MJ, Larrayoz M, Celay J, Vicente C, Fernandez-Galilea M, Larrayoz MJ, Calasanz MJ, Panizo C, Junza A, Han J, Prior C, Fortes P, Pio R, Oyarzabal J, Martinez-Baztan A, Paiva B, Moreno-Aliaga MJ, Odero MD, Agirre X, Yanes O, Prosper F, Martinez-Climent JA. Fresquet V, et al. Among authors: yanes o. Cancer Discov. 2021 May;11(5):1268-1285. doi: 10.1158/2159-8290.CD-20-1065. Epub 2020 Dec 18. Cancer Discov. 2021. PMID: 33355179
97 results