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Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus.
Zhang Y, Wang YF, Yang J, Zhang J, Sun L, Hirankarn N, Pan HF, Lau CS, Chan TM, Lee TL, Leung AM, Mok CC, Zhang L, Shen JJ, Wong SN, Lee KW, Ho MH, Lee PP, Chung BH, Chong CY, Wong RW, Mok MY, Wong WH, Tong KL, Tse NK, Li XP, Avihingsanon Y, Rianthavorn P, Deekajorndej T, Suphapeetiporn K, Shotelersuk V, Ying SK, Fung SK, Lai WM, Wong CM, Ng IO, Garcia-Barcelo MM, Cherny SS, Tam PK, Sham PC, Yang S, Ye DQ, Cui Y, Zhang XJ, Yang W, Lau YL. Zhang Y, et al. Among authors: yang s, yang w, yang j. Arthritis Res Ther. 2015 Mar 20;17(1):67. doi: 10.1186/s13075-015-0577-6. Arthritis Res Ther. 2015. PMID: 25880549 Free PMC article.
Copy number of FCGR3B, which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake.
Willcocks LC, Lyons PA, Clatworthy MR, Robinson JI, Yang W, Newland SA, Plagnol V, McGovern NN, Condliffe AM, Chilvers ER, Adu D, Jolly EC, Watts R, Lau YL, Morgan AW, Nash G, Smith KG. Willcocks LC, et al. Among authors: yang w. J Exp Med. 2008 Jul 7;205(7):1573-82. doi: 10.1084/jem.20072413. Epub 2008 Jun 16. J Exp Med. 2008. PMID: 18559452 Free PMC article.
Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus.
Yang W, Shen N, Ye DQ, Liu Q, Zhang Y, Qian XX, Hirankarn N, Ying D, Pan HF, Mok CC, Chan TM, Wong RW, Lee KW, Mok MY, Wong SN, Leung AM, Li XP, Avihingsanon Y, Wong CM, Lee TL, Ho MH, Lee PP, Chang YK, Li PH, Li RJ, Zhang L, Wong WH, Ng IO, Lau CS, Sham PC, Lau YL; Asian Lupus Genetics Consortium. Yang W, et al. PLoS Genet. 2010 Feb 12;6(2):e1000841. doi: 10.1371/journal.pgen.1000841. PLoS Genet. 2010. PMID: 20169177 Free PMC article.
A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus.
Willcocks LC, Carr EJ, Niederer HA, Rayner TF, Williams TN, Yang W, Scott JA, Urban BC, Peshu N, Vyse TJ, Lau YL, Lyons PA, Smith KG. Willcocks LC, et al. Among authors: yang w. Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7881-5. doi: 10.1073/pnas.0915133107. Epub 2010 Apr 12. Proc Natl Acad Sci U S A. 2010. PMID: 20385827 Free PMC article.
Copy number, linkage disequilibrium and disease association in the FCGR locus.
Niederer HA, Willcocks LC, Rayner TF, Yang W, Lau YL, Williams TN, Scott JA, Urban BC, Peshu N, Dunstan SJ, Hien TT, Phu NH, Padyukov L, Gunnarsson I, Svenungsson E, Savage CO, Watts RA, Lyons PA, Clayton DG, Smith KG. Niederer HA, et al. Among authors: yang w. Hum Mol Genet. 2010 Aug 15;19(16):3282-94. doi: 10.1093/hmg/ddq216. Epub 2010 May 27. Hum Mol Genet. 2010. PMID: 20508037 Free PMC article.
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