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Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis.
Li Y, Schwabe RF, DeVries-Seimon T, Yao PM, Gerbod-Giannone MC, Tall AR, Davis RJ, Flavell R, Brenner DA, Tabas I. Li Y, et al. Among authors: yao pm. J Biol Chem. 2005 Jun 10;280(23):21763-72. doi: 10.1074/jbc.M501759200. Epub 2005 Apr 11. J Biol Chem. 2005. PMID: 15826936 Free article.
Macrophages deficient in CTP:Phosphocholine cytidylyltransferase-alpha are viable under normal culture conditions but are highly susceptible to free cholesterol-induced death. Molecular genetic evidence that the induction of phosphatidylcholine biosynthesis in free cholesterol-loaded macrophages is an adaptive response.
Zhang D, Tang W, Yao PM, Yang C, Xie B, Jackowski S, Tabas I. Zhang D, et al. Among authors: yao pm. J Biol Chem. 2000 Nov 10;275(45):35368-76. doi: 10.1074/jbc.M007099200. J Biol Chem. 2000. PMID: 10944538 Free article.
15 results