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6,052 results

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Page 1
Discovery of a tetracyclic quinoxaline derivative as a potent and orally active multifunctional drug candidate for the treatment of neuropsychiatric and neurological disorders.
Li P, Zhang Q, Robichaud AJ, Lee T, Tomesch J, Yao W, Beard JD, Snyder GL, Zhu H, Peng Y, Hendrick JP, Vanover KE, Davis RE, Mates S, Wennogle LP. Li P, et al. Among authors: yao w. J Med Chem. 2014 Mar 27;57(6):2670-82. doi: 10.1021/jm401958n. Epub 2014 Mar 5. J Med Chem. 2014. PMID: 24559051
Discovery of novel alpha7 nicotinic receptor antagonists.
Peng Y, Zhang Q, Snyder GL, Zhu H, Yao W, Tomesch J, Papke RL, O'Callaghan JP, Welsh WJ, Wennogle LP. Peng Y, et al. Among authors: yao w. Bioorg Med Chem Lett. 2010 Aug 15;20(16):4825-30. doi: 10.1016/j.bmcl.2010.06.103. Epub 2010 Jun 25. Bioorg Med Chem Lett. 2010. PMID: 20638843 Free PMC article.
Discovery of Potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases.
Li P, Zheng H, Zhao J, Zhang L, Yao W, Zhu H, Beard JD, Ida K, Lane W, Snell G, Sogabe S, Heyser CJ, Snyder GL, Hendrick JP, Vanover KE, Davis RE, Wennogle LP. Li P, et al. Among authors: yao w. J Med Chem. 2016 Feb 11;59(3):1149-64. doi: 10.1021/acs.jmedchem.5b01751. Epub 2016 Feb 2. J Med Chem. 2016. PMID: 26789933
Preclinical profile of ITI-214, an inhibitor of phosphodiesterase 1, for enhancement of memory performance in rats.
Snyder GL, Prickaerts J, Wadenberg ML, Zhang L, Zheng H, Yao W, Akkerman S, Zhu H, Hendrick JP, Vanover KE, Davis R, Li P, Mates S, Wennogle LP. Snyder GL, et al. Among authors: yao w. Psychopharmacology (Berl). 2016 Sep;233(17):3113-24. doi: 10.1007/s00213-016-4346-2. Epub 2016 Jun 24. Psychopharmacology (Berl). 2016. PMID: 27342643 Free PMC article.
Acute Enhancement of Cardiac Function by Phosphodiesterase Type 1 Inhibition.
Hashimoto T, Kim GE, Tunin RS, Adesiyun T, Hsu S, Nakagawa R, Zhu G, O'Brien JJ, Hendrick JP, Davis RE, Yao W, Beard D, Hoxie HR, Wennogle LP, Lee DI, Kass DA. Hashimoto T, et al. Among authors: yao w. Circulation. 2018 Oct 30;138(18):1974-1987. doi: 10.1161/CIRCULATIONAHA.117.030490. Circulation. 2018. PMID: 30030415 Free PMC article.
Selective Phosphodiesterase 1 Inhibition Ameliorates Vascular Function, Reduces Inflammatory Response, and Lowers Blood Pressure in Aging Animals.
Golshiri K, Ataei Ataabadi E, Rubio-Beltran E, Dutheil S, Yao W, Snyder GL, Davis RE, van der Pluijm I, Brandt R, Van den Berg-Garrelds IM, MaassenVanDenBrink A, de Vries R, Danser AHJ, Roks AJM. Golshiri K, et al. Among authors: yao w. J Pharmacol Exp Ther. 2021 Aug;378(2):173-183. doi: 10.1124/jpet.121.000628. Epub 2021 Jun 7. J Pharmacol Exp Ther. 2021. PMID: 34099502
Angioleiomyoma in the inferior vena cava: A rare case report.
Yao W, Zhai A, Fang M, Shang X. Yao W, et al. Asian J Surg. 2024 May 16:S1015-9584(24)00847-9. doi: 10.1016/j.asjsur.2024.04.165. Online ahead of print. Asian J Surg. 2024. PMID: 38760207 No abstract available.
6,052 results