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Antibody to granulocyte macrophage colony-stimulating factor reduces the number of activated tissue macrophages and improves left ventricular function after myocardial infarction in a rat coronary artery ligation model.
Kellar RS, Lancaster JJ, Thai HM, Juneman E, Johnson NM, Byrne HG, Stansifer M, Arsanjani R, Baer M, Bebbington C, Flashner M, Yarranton G, Goldman S. Kellar RS, et al. Among authors: yarranton g. J Cardiovasc Pharmacol. 2011 May;57(5):568-74. doi: 10.1097/FJC.0b013e318213258b. J Cardiovasc Pharmacol. 2011. PMID: 21326109
The eosinophil surface receptor epidermal growth factor-like module containing mucin-like hormone receptor 1 (EMR1): a novel therapeutic target for eosinophilic disorders.
Legrand F, Tomasevic N, Simakova O, Lee CC, Wang Z, Raffeld M, Makiya MA, Palath V, Leung J, Baer M, Yarranton G, Maric I, Bebbington C, Klion AD. Legrand F, et al. Among authors: yarranton g. J Allergy Clin Immunol. 2014 May;133(5):1439-47, 1447.e1-8. doi: 10.1016/j.jaci.2013.11.041. Epub 2014 Feb 13. J Allergy Clin Immunol. 2014. PMID: 24530099 Free PMC article. Clinical Trial.
Targeting EphA3 inhibits cancer growth by disrupting the tumor stromal microenvironment.
Vail ME, Murone C, Tan A, Hii L, Abebe D, Janes PW, Lee FT, Baer M, Palath V, Bebbington C, Yarranton G, Llerena C, Garic S, Abramson D, Cartwright G, Scott AM, Lackmann M. Vail ME, et al. Among authors: yarranton g. Cancer Res. 2014 Aug 15;74(16):4470-81. doi: 10.1158/0008-5472.CAN-14-0218. Cancer Res. 2014. PMID: 25125683
CD10 is a key enzyme involved in the activation of tumor-activated peptide prodrug CPI-0004Na and novel analogues: implications for the design of novel peptide prodrugs for the therapy of CD10+ tumors.
Pan C, Cardarelli PM, Nieder MH, Pickford LB, Gangwar S, King DJ, Yarranton GT, Buckman D, Roscoe W, Zhou F, Salles A, Chen TH, Horgan K, Wang YH, Nguyen T, Bebbington CR. Pan C, et al. Cancer Res. 2003 Sep 1;63(17):5526-31. Cancer Res. 2003. PMID: 14500390
58 results