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Anti-PD-1 antibodies recognizing the membrane-proximal region are PD-1 agonists that can down-regulate inflammatory diseases.
Sci Immunol. 2023 Jan 13;8(79):eadd4947. doi: 10.1126/sciimmunol.add4947. Epub 2023 Jan 13.
Sci Immunol. 2023.
PMID: 36638191
Inactivation of the PD-1-Dependent Immunoregulation in Mice Exacerbates Contact Hypersensitivity Resembling Immune-Related Adverse Events.
Ashoori MD, Suzuki K, Tokumaru Y, Ikuta N, Tajima M, Honjo T, Ohta A.
Ashoori MD, et al. Among authors: tokumaru y.
Front Immunol. 2021 Jan 27;11:618711. doi: 10.3389/fimmu.2020.618711. eCollection 2020.
Front Immunol. 2021.
PMID: 33584713
Free PMC article.
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