Yu F - Search Results

1

A truncated receptor-binding domain of MERS-CoV spike protein potently inhibits MERS-CoV infection and induces strong neutralizing antibody responses: implication for developing therapeutics and vaccines.

Du L, Kou Z, Ma C, Tao X, Wang L, Zhao G, Chen Y, Yu F, Tseng CT, Zhou Y, Jiang S. Du L, et al. Among authors: yu f. PLoS One. 2013 Dec 4;8(12):e81587. doi: 10.1371/journal.pone.0081587. eCollection 2013. PLoS One. 2013. PMID: 24324708 Free PMC article.

2

Approaches for identification of HIV-1 entry inhibitors targeting gp41 pocket.

Yu F, Lu L, Du L, Zhu X, Debnath AK, Jiang S. Yu F, et al. Viruses. 2013 Jan 11;5(1):127-49. doi: 10.3390/v5010127. Viruses. 2013. PMID: 23344560 Free PMC article. Review.

3

Tactics used by HIV-1 to evade host innate, adaptive, and intrinsic immunities.

Lu L, Yu F, DU LY, Xu W, Jiang SB. Lu L, et al. Among authors: yu f. Chin Med J (Engl). 2013 Jun;126(12):2374-9. Chin Med J (Engl). 2013. PMID: 23786957 Review.

4

A safe and convenient pseudovirus-based inhibition assay to detect neutralizing antibodies and screen for viral entry inhibitors against the novel human coronavirus MERS-CoV.

Zhao G, Du L, Ma C, Li Y, Li L, Poon VK, Wang L, Yu F, Zheng BJ, Jiang S, Zhou Y. Zhao G, et al. Among authors: yu f. Virol J. 2013 Aug 26;10:266. doi: 10.1186/1743-422X-10-266. Virol J. 2013. PMID: 23978242 Free PMC article.

5

F(ab')2 fragment of a gp41 NHR-trimer-induced IgM monoclonal antibody neutralizes HIV-1 infection and blocks viral fusion by targeting the conserved gp41 pocket.

Lu L, Wei M, Chen Y, Xiong W, Yu F, Qi Z, Jiang S, Pan C. Lu L, et al. Among authors: yu f. Microbes Infect. 2013 Nov;15(13):887-94. doi: 10.1016/j.micinf.2013.10.001. Epub 2013 Oct 17. Microbes Infect. 2013. PMID: 24141089 Free article.

6

ADS-J1 inhibits HIV-1 infection and membrane fusion by targeting the highly conserved pocket in the gp41 NHR-trimer.

Yu F, Lu L, Liu Q, Yu X, Wang L, He E, Zou P, Du L, Sanders RW, Liu S, Jiang S. Yu F, et al. Among authors: yu x. Biochim Biophys Acta. 2014 May;1838(5):1296-305. doi: 10.1016/j.bbamem.2013.12.022. Epub 2014 Jan 3. Biochim Biophys Acta. 2014. PMID: 24388952 Free article.

7

Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor.

Lu L, Liu Q, Zhu Y, Chan KH, Qin L, Li Y, Wang Q, Chan JF, Du L, Yu F, Ma C, Ye S, Yuen KY, Zhang R, Jiang S. Lu L, et al. Among authors: yu f. Nat Commun. 2014;5:3067. doi: 10.1038/ncomms4067. Nat Commun. 2014. PMID: 24473083 Free PMC article.

8

Artificial peptides conjugated with cholesterol and pocket-specific small molecules potently inhibit infection by laboratory-adapted and primary HIV-1 isolates and enfuvirtide-resistant HIV-1 strains.

Wang C, Shi W, Cai L, Lu L, Yu F, Wang Q, Jiang X, Xu X, Wang K, Xu L, Jiang S, Liu K. Wang C, et al. Among authors: yu f. J Antimicrob Chemother. 2014 Jun;69(6):1537-45. doi: 10.1093/jac/dku010. Epub 2014 Feb 4. J Antimicrob Chemother. 2014. PMID: 24500189

9

Hydrophobic mutations in buried polar residues enhance HIV-1 gp41 N-terminal heptad repeat-C-terminal heptad repeat interactions and C-peptides' anti-HIV activity.

Zheng B, Wang K, Lu L, Yu F, Cheng M, Jiang S, Liu K, Cai L. Zheng B, et al. Among authors: yu f. AIDS. 2014 Jun 1;28(9):1251-60. doi: 10.1097/QAD.0000000000000255. AIDS. 2014. PMID: 24625369

10

HIV-1 impairs human retinal pigment epithelial barrier function: possible association with the pathogenesis of HIV-associated retinopathy.

Tan S, Duan H, Xun T, Ci W, Qiu J, Yu F, Zhao X, Wu L, Li L, Lu L, Jiang S, Liu S. Tan S, et al. Among authors: yu f. Lab Invest. 2014 Jul;94(7):777-87. doi: 10.1038/labinvest.2014.72. Epub 2014 May 19. Lab Invest. 2014. PMID: 24840331 Free article.

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