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N-Methyl-3-(tetrahydro-2H-pyran-4-yl)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamides as a novel class of cannabinoid receptors agonists with low CNS penetration.
Wei Z, Yang H, Liu Z, Tremblay M, Johnstone S, Béha S, Yue SY, Srivastava S, Tomaszewski MJ, Brown W, Walpole C, St-Onge S, Lessard E, Archambault AJ, Groblewski T, Pagé D. Wei Z, et al. Among authors: yue sy. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3884-9. doi: 10.1016/j.bmcl.2012.04.128. Epub 2012 May 4. Bioorg Med Chem Lett. 2012. PMID: 22607668
New diarylmethylpiperazines as potent and selective nonpeptidic delta opioid receptor agonists with increased In vitro metabolic stability.
Plobeck N, Delorme D, Wei ZY, Yang H, Zhou F, Schwarz P, Gawell L, Gagnon H, Pelcman B, Schmidt R, Yue SY, Walpole C, Brown W, Zhou E, Labarre M, Payza K, St-Onge S, Kamassah A, Morin PE, Projean D, Ducharme J, Roberts E. Plobeck N, et al. Among authors: yue sy. J Med Chem. 2000 Oct 19;43(21):3878-94. doi: 10.1021/jm000228x. J Med Chem. 2000. PMID: 11052793
N,N-Diethyl-4-(phenylpiperidin-4-ylidenemethyl)benzamide: a novel, exceptionally selective, potent delta opioid receptor agonist with oral bioavailability and its analogues.
Wei ZY, Brown W, Takasaki B, Plobeck N, Delorme D, Zhou F, Yang H, Jones P, Gawell L, Gagnon H, Schmidt R, Yue SY, Walpole C, Payza K, St-Onge S, Labarre M, Godbout C, Jakob A, Butterworth J, Kamassah A, Morin PE, Projean D, Ducharme J, Roberts E. Wei ZY, et al. Among authors: yue sy. J Med Chem. 2000 Oct 19;43(21):3895-905. doi: 10.1021/jm000229p. J Med Chem. 2000. PMID: 11052794
70 results