Yuen SL - Search Results

1

Advancements in a FRET Biosensor for Live-Cell Fluorescence-Lifetime High-Throughput Screening of Alpha-Synuclein.

Braun AR, Kochen NN, Yuen SL, Liao EE, Cornea RL, Thomas DD, Sachs JN. Braun AR, et al. Among authors: yuen sl. ASN Neuro. 2023 Jan-Dec;15:17590914231184086. doi: 10.1177/17590914231184086. ASN Neuro. 2023. PMID: 37428128 Free PMC article.

2

Fluorescence lifetime FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators.

Roopnarine O, Yuen SL, Thompson AR, Roelike LN, Rebbeck RT, Bidwell PA, Aldrich CC, Cornea RL, Thomas DD. Roopnarine O, et al. Among authors: yuen sl. Sci Rep. 2023 Jul 1;13(1):10673. doi: 10.1038/s41598-023-37704-x. Sci Rep. 2023. PMID: 37393380 Free PMC article.

3

HTS driven by fluorescence lifetime detection of FRET identifies activators and inhibitors of cardiac myosin.

Muretta JM, Rajasekaran D, Blat Y, Little S, Myers M, Nair C, Burdekin B, Yuen SL, Jimenez N, Guhathakurta P, Wilson A, Thompson AR, Surti N, Connors D, Chase P, Harden D, Barbieri CM, Adam L, Thomas DD. Muretta JM, et al. Among authors: yuen sl. SLAS Discov. 2023 Jul;28(5):223-232. doi: 10.1016/j.slasd.2023.06.001. Epub 2023 Jun 10. SLAS Discov. 2023. PMID: 37307989 Free PMC article.

4

The selective RyR2 inhibitor ent-verticilide suppresses atrial fibrillation susceptibility caused by Pitx2 deficiency.

Kim K, Blackwell DJ, Yuen SL, Thorpe MP, Johnston JN, Cornea RL, Knollmann BC. Kim K, et al. Among authors: yuen sl. J Mol Cell Cardiol. 2023 Jul;180:1-9. doi: 10.1016/j.yjmcc.2023.04.005. Epub 2023 Apr 18. J Mol Cell Cardiol. 2023. PMID: 37080450

5

Indirubin Inhibits TRAIL-Induced Activation of Death Receptor 5 in Jurkat Cells.

Young MC, Vunnam N, Rebbeck RT, Yuen SL, Thomas DD, Sachs JN. Young MC, et al. Among authors: yuen sl. Nat Prod Commun. 2023 Jan;18(1):10.1177/1934578x221144580. doi: 10.1177/1934578x221144580. Epub 2023 Jan 11. Nat Prod Commun. 2023. PMID: 37063699 Free PMC article.

6

FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators.

Roopnarine O, Yuen SL, Thompson AR, Roelike LN, Rebbeck RT, Bidwell PA, Aldrich CC, Cornea RL, Thomas DD. Roopnarine O, et al. Among authors: yuen sl. Res Sq [Preprint]. 2023 Feb 28:rs.3.rs-2596384. doi: 10.21203/rs.3.rs-2596384/v1. Res Sq. 2023. PMID: 36909610 Free PMC article. Updated. Preprint.

7

FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators.

Roopnarine O, Yuen SL, Thompson AR, Roelike LN, Rebbeck RT, Bidwell PA, Aldrich CC, Cornea RL, Thomas DD. Roopnarine O, et al. Among authors: yuen sl. bioRxiv [Preprint]. 2023 Feb 22:2023.02.22.529557. doi: 10.1101/2023.02.22.529557. bioRxiv. 2023. PMID: 36865289 Free PMC article. Updated. Preprint.

8

A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A.

Simon M, Yang J, Gigas J, Earley EJ, Hillpot E, Zhang L, Zagorulya M, Tombline G, Gilbert M, Yuen SL, Pope A, Van Meter M, Emmrich S, Firsanov D, Athreya A, Biashad SA, Han J, Ryu S, Tare A, Zhu Y, Hudgins A, Atzmon G, Barzilai N, Wolfe A, Moody K, Garcia BA, Robbins PD, Vijg J, Seluanov A, Suh Y, Gorbunova V. Simon M, et al. Among authors: yuen sl. EMBO J. 2023 Feb 1;42(3):e113326. doi: 10.15252/embj.2022113326. EMBO J. 2023. PMID: 36722290 Free PMC article.

9

A Large-Scale High-Throughput Screen for Modulators of SERCA Activity.

Bidwell PA, Yuen SL, Li J, Berg K, Rebbeck RT, Aldrich CC, Roopnarine O, Cornea RL, Thomas DD. Bidwell PA, et al. Among authors: yuen sl. Biomolecules. 2022 Nov 30;12(12):1789. doi: 10.3390/biom12121789. Biomolecules. 2022. PMID: 36551215 Free PMC article.

10

New N-aryl-N-alkyl-thiophene-2-carboxamide compound enhances intracellular Ca²⁺ dynamics by increasing SERCA2a Ca²⁺ pumping.

Nikolaienko R, Bovo E, Yuen SL, Treinen LM, Berg K, Aldrich CC, Thomas DD, Cornea RL, Zima AV. Nikolaienko R, et al. Among authors: yuen sl. Biophys J. 2023 Jan 17;122(2):386-396. doi: 10.1016/j.bpj.2022.12.002. Epub 2022 Dec 5. Biophys J. 2023. PMID: 36463408 Free PMC article.

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