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Page 1
Lipopolysaccharide administration increases the susceptibility of mitochondrial permeability transition pore opening via altering adenine nucleotide translocase conformation in the mouse liver.
J Toxicol Sci. 2023;48(2):65-73. doi: 10.2131/jts.48.65.
J Toxicol Sci. 2023.
PMID: 36725022
Free article.
New in vitro screening system to detect drug-induced liver injury using a culture plate with low drug sorption and high oxygen permeability.
Takemura A, Ishii S, Ikeyama Y, Esashika K, Takahashi J, Ito K.
Takemura A, et al. Among authors: ikeyama y.
Drug Metab Pharmacokinet. 2023 Oct;52:100511. doi: 10.1016/j.dmpk.2023.100511. Epub 2023 Apr 26.
Drug Metab Pharmacokinet. 2023.
PMID: 37531708
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Functional modulation of liver mitochondria in lipopolysaccharide/drug co-treated rat liver injury model.
Arakawa K, Ikeyama Y, Sato T, Segawa M, Sekine S, Ito K.
Arakawa K, et al. Among authors: ikeyama y.
J Toxicol Sci. 2019;44(12):833-843. doi: 10.2131/jts.44.833.
J Toxicol Sci. 2019.
PMID: 31813902
Free article.
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Hypoxia/reoxygenation exacerbates drug-induced cytotoxicity by opening mitochondrial permeability transition pore: Possible application for toxicity screening.
Ikeyama Y, Sato T, Takemura A, Sekine S, Ito K.
Ikeyama Y, et al.
Toxicol In Vitro. 2020 Sep;67:104889. doi: 10.1016/j.tiv.2020.104889. Epub 2020 May 14.
Toxicol In Vitro. 2020.
PMID: 32417306
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Successful energy shift from glycolysis to mitochondrial oxidative phosphorylation in freshly isolated hepatocytes from humanized mice liver.
Ikeyama Y, Sato T, Takemura A, Sekine S, Ito K.
Ikeyama Y, et al.
Toxicol In Vitro. 2020 Jun;65:104785. doi: 10.1016/j.tiv.2020.104785. Epub 2020 Jan 25.
Toxicol In Vitro. 2020.
PMID: 31991145
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